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5.3.1.6: ribose-5-phosphate isomerase

This is an abbreviated version!
For detailed information about ribose-5-phosphate isomerase, go to the full flat file.

Word Map on EC 5.3.1.6

Reaction

D-ribose 5-phosphate
=
D-ribulose 5-phosphate

Synonyms

5-phosphate ketol-isomerase, 5-Phosphoribose isomerase, CTRPI, CTRpiB, D-Ribose 5-phosphate isomerase, D-ribose-5-phosphate isomerase, D-ribose-5-phosphate isomerase A, D-ribose-5-phosphate isomerase B, D-ribose-5-phosphate ketol-isomerase, D-xylose ketol-isomerase, EcRpiB, Isomerase, ribose phosphate, LINJ_28_2100, LMJF_28_1970, MJ1603, MtRpiB, Phosphopentoisomerase, Phosphopentose isomerase, Phosphoriboisomerase, ribose 5-phosphate isomerase A, Ribose phosphate isomerase, Ribose-5-P isomerase, ribose-5-phosphate isomerase, ribose-5-phosphate isomerase B, ribose-5-phosphate isomerase type B, Ribosephosphate isomerase A, Ribosephosphate isomerase B, RPI, RPI2 protein, RpiA, RpiB, SMU1234, SMU2142, Tc00.1047053509199.24, TM1080, type B ribose 5-phosphate isomerase, type B ribose-5-phosphate isomerase, type B Rpi

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.1 Interconverting aldoses and ketoses, and related compounds
                5.3.1.6 ribose-5-phosphate isomerase

Temperature Stability

Temperature Stability on EC 5.3.1.6 - ribose-5-phosphate isomerase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100
stability and integrity up to, needs at least 250 mM NaCl to maintain its hyperthermostability
35 - 50
-
enzyme activity is stable for 48 h at 35°C, and shows half-lives of 15 h at 40°C, and 6 h at 50°C
50
-
half-life 96 h
57
-
1 h, 50% loss of activity
60 - 75
the half-lives of the wild type enzyme at 60°C, 65°C, 70°C, 75°C, and 80°C are 11, 7.0, 4.2, 1.5, and 0.6 h, respectively
60 - 80
-
the purified enzyme at 0.1 mg/ml is very stable at 60 and 70°C but is deactivated at 80°C. The enzyme shows half lifetimes of 70.8, 53.1, 6.4, and 1.2 h at 60, 70, 80, and 90°C, respectively
91
-
1 h, 50% loss of activity