5.3.1.6: ribose-5-phosphate isomerase

This is an abbreviated version!
For detailed information about ribose-5-phosphate isomerase, go to the full flat file.

Reaction

Synonyms

5-phosphate ketol-isomerase, 5-Phosphoribose isomerase, CTRPI, CTRpiB, D-Ribose 5-phosphate isomerase, D-ribose-5-phosphate isomerase, D-ribose-5-phosphate isomerase A, D-ribose-5-phosphate isomerase B, D-ribose-5-phosphate ketol-isomerase, D-xylose ketol-isomerase, EcRpiB, Isomerase, ribose phosphate, LINJ_28_2100, LMJF_28_1970, MJ1603, MtRpiB, Phosphopentoisomerase, Phosphopentose isomerase, Phosphoriboisomerase, ribose 5-phosphate isomerase A, Ribose phosphate isomerase, Ribose-5-P isomerase, ribose-5-phosphate isomerase, ribose-5-phosphate isomerase B, ribose-5-phosphate isomerase type B, Ribosephosphate isomerase A, Ribosephosphate isomerase B, RPI, RPI2 protein, RpiA, RpiB, SMU1234, SMU2142, Tc00.1047053509199.24, TM1080, type B ribose 5-phosphate isomerase, type B ribose-5-phosphate isomerase, type B Rpi

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.1 Interconverting aldoses and ketoses, and related compounds

                5.3.1.6 ribose-5-phosphate isomerase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
8	Activating Compound
38859	AA Sequence
5	Application
1	CAS Registry Number
29	Cloned(Commentary)
22	Crystallization (Commentary)
291	Disease/ Diagnostics
10	General Information
8	General Stability
22	IC50 Value
114	Inhibitors
27	kcat/KM [mM/s]
27	Ki Value [mM]
87	KM Value [mM]
9	Localization
9	Metals/Ions
55	Molecular Weight [Da]
34	Natural Substrates/ Products (Substrates)
219	Organism
19	Pathway
133	PDB ID
22	pH Optimum
4	pH Range
2	pH Stability
6	pI Value
46	Protein Variants
29	Purification (Commentary)
1	Reaction
2	Reaction Type
101	Reference
33	Source Tissue
68	Specific Activity [micromol/min/mg]
7	Storage Stability
195	Substrates and Products (Substrate)
39	Subunits
108	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
4	Temperature Range [°C]
19	Temperature Stability [°C]
66	Turnover Number [1/s]

Application

print visible entries

print all entries

Application on EC 5.3.1.6 - ribose-5-phosphate isomerase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Application Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

medicine

Homo sapiens

P49247

RPIA is significantly elevated in colorectal. RPIA modulates cell proliferation and oncogenicity via activation of beta-catenin in colon cancer cell lines. RPIA enters the nucleus to form a complex with the adenomatous polyposis coli and beta-catenin, the association protects beta-catenin by preventing its phosphorylation, ubiquitination, and subsequent degradation. The C-terminus of RPIA (amino acids 290 to 311) is necessary for RPIA-mediated tumorigenesis

749044

synthesis

4 entries

synthesis

Acetivibrio thermocellus

-

production of D-allose from D-psicose by enzyme. At pH 7.5 and 50°C, synthesis of 165 g D-allose per l within 6 h

678884

synthesis

Streptococcus pneumoniae

-

RpiB is a potential producer of L-form monosaccharides

717008

synthesis

Acetivibrio thermocellus

-

production of allose from fructose by a one-pot reaction using Flavonifractor plautii D-allulose 3-epimerase and Clostridium thermocellum ribose 5-phosphate isomerase. Under optimal reaction conditions of pH 7.5, 60°C, 0.1 g/l epimerase, 12 g/l isomerase, and 600 g/l fructose in the presence of 1 mM Co2+, 79 g/l allose can be produced within 2 h, with a conversion yield of 13%

748388

synthesis

Acetivibrio thermocellus ATCC 27405

-

production of allose from fructose by a one-pot reaction using Flavonifractor plautii D-allulose 3-epimerase and Clostridium thermocellum ribose 5-phosphate isomerase. Under optimal reaction conditions of pH 7.5, 60°C, 0.1 g/l epimerase, 12 g/l isomerase, and 600 g/l fructose in the presence of 1 mM Co2+, 79 g/l allose can be produced within 2 h, with a conversion yield of 13%

-