5.3.1.5: xylose isomerase
This is an abbreviated version!
For detailed information about xylose isomerase, go to the full flat file.
Word Map on EC 5.3.1.5
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5.3.1.5
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isomerization
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biomass
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d-glucose
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xylitol
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xylulokinase
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pentose
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lignocellulosic
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isomerases
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syrup
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corn
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gi
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d-fructose
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rubiginosus
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bioethanol
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piromyces
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arthrobacter
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l-arabinose
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synthesis
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actinoplanes
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high-fructose
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xylose-fermenting
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transaldolase
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saccharification
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thermoanaerobacter
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co-fermentation
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hemicellulosic
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thermoanaerobacterium
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neapolitana
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stipitis
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energy production
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orpinomyces
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thermosulfurogenes
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xylose-utilizing
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diauxic
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food industry
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nutrition
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biotechnology
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degradation
- 5.3.1.5
-
isomerization
- biomass
- d-glucose
- xylitol
- xylulokinase
- pentose
-
lignocellulosic
- isomerases
- syrup
- corn
- gi
- d-fructose
- rubiginosus
-
bioethanol
- piromyces
- arthrobacter
- l-arabinose
- synthesis
- actinoplanes
-
high-fructose
-
xylose-fermenting
- transaldolase
-
saccharification
- thermoanaerobacter
-
co-fermentation
-
hemicellulosic
- thermoanaerobacterium
- neapolitana
- stipitis
- energy production
- orpinomyces
- thermosulfurogenes
-
xylose-utilizing
-
diauxic
- food industry
- nutrition
- biotechnology
- degradation
Reaction
Synonyms
D-XI, D-xylose aldose-ketose-isomerase, D-xylose isomerase, D-Xylose ketoisomerase, D-xylose ketol isomerase, D-xylose ketol-isomerase, D-xylose: ketol-isomerase, D-xylulose keto-isomerase, glucose isomerase, glucose/xylose isomerase, GXI, Isomerase, xylose, Maxazyme, Optisweet, SDXyI, Spezyme, Sweetase, Sweetzyme, Sweetzyme Q, Swetase, T80 xylose isomerase, TcaXI, TNXI, TthXI, XI, XYLA, XylC, xylose (glucose) isomerase, xylose isomerase
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Inhibitors
Inhibitors on EC 5.3.1.5 - xylose isomerase
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D-glyceraldehyde
competitive inhibition of the isomerization of D-xylose
Ca2+
less than 10% residual activity for D-xylose and D-glucose isomerase activities of XylA at 1 mM Zn2+
Cu2+
complete inhibition of D-xylose and D-glucose isomerase activities of XylA at 1 mM Cu2+
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suppressed enzyme synthesis by increased content from 0.1 to 1.5%, productivity maxima at 0.1%, if D-xylose is the carbon source: D-glucose supplementation suppresses formation of xylose isomerase
D-glucose
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suppressed enzyme synthesis by increased D-glucose content from 0.1 to 1.5%, productivity maxima at 1.0%
D-glucose
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suppressed enzyme synthesis by increased D-glucose content from 0.1 to 1.5%, productivity maxima at 0.1% D-glucose, if D-xylose is the carbon source D-glucose supplementation suppresses formation of xylose isomerase
D-sorbitol
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competitive against D-glucose, D-xylose, and D-ribose. Co2+ and Mg2+ prevent inhibition
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slow-binding competitive inhibitor with glucose as substrate
D-Threonohydroxamic acid
competitive inhibitor, complete inhibition at 0.5 mM
EDTA
less than 10% residual activity for D-xylose and D-glucose isomerase activities of XylA at 1 mM Zn2+
EDTA
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Mn2+, Mg2+, or Co2+ restore 60-70% of the original xylose isomerase activity
Tris(hydroxymethyl)aminomethane
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strong inhibition of D-glucose isomerization, slight inhibition of D-xylose isomerization, competitive
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inhibits in vitro xylose isomerase activity severely and competitively
Zn2+
less than 10% residual activity for D-glucose isomerase activity and about 10% residual activity for D-xylose activity of XylA at 1 mM Zn2+