5.3.1.25: L-fucose isomerase
This is an abbreviated version!
For detailed information about L-fucose isomerase, go to the full flat file.
Word Map on EC 5.3.1.25
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5.3.1.25
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l-fuculose
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isomerization
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d-ribulose
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l-1,2-propanediol
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aerogenes
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d-altrose
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noninducible
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lactaldehyde
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dihydroxyacetone
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propanediol
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ribitol
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irretrievably
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synthesis
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medicine
- 5.3.1.25
- l-fuculose
-
isomerization
- d-ribulose
- l-1,2-propanediol
- aerogenes
- d-altrose
-
noninducible
- lactaldehyde
- dihydroxyacetone
-
propanediol
- ribitol
-
irretrievably
- synthesis
- medicine
Reaction
Synonyms
D-Arabinose (L-Fucose) isomerase, D-Arabinose isomerase, EC 5.3.1.3, FcsI, FucI, Fucose isomerase, Isomerase, L-fucose, L-Fucose isomerase, L-fucose ketol-isomerase
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medicine
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the Streptococcus pneumoniae fucose-processing pathway has a nonmetabolic role in the interaction of this bacterium with its human host
synthesis
two-step enzymatic strategy for the synthesis of 6-deoxy-L-sorbose. First, the isomerization of L-fucose to L-fuculose,and the epimerization of L-fuculose to 6-deoxy-L-sorbose catalyzed by D-tagatose 3-epimerase are coupled with the targeted phosphorylation of 6-deoxy-L-sorbose by human fructose kinase in a one-pot reaction. In the second reaction step, the phosphate group of the 6-deoxy-L-sorbose 1-phosphate is hydrolyzed with acid phosphatase to produce 6-deoxy-L-sorbose in 81% yield with regard to L-fucose