5.3.1.25: L-fucose isomerase

This is an abbreviated version!
For detailed information about L-fucose isomerase, go to the full flat file.

Word Map on EC 5.3.1.25

Reaction

L-fucopyranose
=
L-Fuculose

Synonyms

Isomerase, L-fucose, Fucose isomerase, D-Arabinose isomerase, D-Arabinose (L-Fucose) isomerase, EC 5.3.1.3, L-Fucose isomerase, L-fucose ketol-isomerase, FucI, FcsI

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.1 Interconverting aldoses and ketoses, and related compounds
                5.3.1.25 L-fucose isomerase

Application

Application on EC 5.3.1.25 - L-fucose isomerase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
medicine
-
the Streptococcus pneumoniae fucose-processing pathway has a nonmetabolic role in the interaction of this bacterium with its human host
synthesis
two-step enzymatic strategy for the synthesis of 6-deoxy-L-sorbose. First, the isomerization of L-fucose to L-fuculose,and the epimerization of L-fuculose to 6-deoxy-L-sorbose catalyzed by D-tagatose 3-epimerase are coupled with the targeted phosphorylation of 6-deoxy-L-sorbose by human fructose kinase in a one-pot reaction. In the second reaction step, the phosphate group of the 6-deoxy-L-sorbose 1-phosphate is hydrolyzed with acid phosphatase to produce 6-deoxy-L-sorbose in 81% yield with regard to L-fucose