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5.3.1.23: S-methyl-5-thioribose-1-phosphate isomerase

This is an abbreviated version!
For detailed information about S-methyl-5-thioribose-1-phosphate isomerase, go to the full flat file.

Word Map on EC 5.3.1.23

Reaction

S-methyl-5-thio-alpha-D-ribose 1-phosphate
=
S-methyl-5-thio-D-ribulose 1-phosphate

Synonyms

1-PMTR isomerase, 5'-methylthioribose-1-phosphate isomerase, 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase, 5-methylthioribose 1-phosphate isomerase, 5-methylthioribose-1-phosphate isomerase, Bs-M1Pi, Isomerase, methylthioribose 1-phosphate, M1Pi, methylthioribose-1-phosphate isomerase, Meu1p, MRDI, MRI1, Mri1p, mtnA, MTR-1-P, MTR-1-P isomerase, PH0702, PhM1Pi, Ypr118w, Ypr118wp

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.1 Interconverting aldoses and ketoses, and related compounds
                5.3.1.23 S-methyl-5-thioribose-1-phosphate isomerase

Reference

topprint

Reference on EC 5.3.1.23 - S-methyl-5-thioribose-1-phosphate isomerase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Trackman, P.C.; Abeles, R.H.
Methionine synthesis from 5'-S-methylthioaenosine. Resolution of enzyme activities and identification of 1-phospho-5-S-methylthioribulose
J. Biol. Chem.
258
6717-6720
1983
Rattus norvegicus
Manually annotated by BRENDA team
Furfine, E.S.; Abeles, R.H.
Intermediates in the conversion of 5'-S-methylthioadenosine to methionine in Klebsiella pneumoniae
J. Biol. Chem.
263
9598-9606
1988
Klebsiella pneumoniae
Manually annotated by BRENDA team
Ghoda, L.Y.; Savarese, T.M.; Dexter, D.L.; Parks, R.E.; Trackman, P.C.; Abeles, R.H.
Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma
J. Biol. Chem.
259
6715-6719
1984
Homo sapiens
Manually annotated by BRENDA team
Tamura, H.; Matsumura, H.; Inoue, T.; Ashida, H.; Saito, Y.; Yokota, A.; Kai, Y.
Crystallization and preliminary X-ray analysis of methylthioribose-1-phosphate isomerase from Bacillus subtilis
Acta Crystallogr. Sect. F
F61
595-598
2005
Bacillus subtilis
Manually annotated by BRENDA team
Bumann, M.; Djafarzadeh, S.; Oberholzer, A.E.; Bigler, P.; Altmann, M.; Trachsel, H.; Baumann, U.
Crystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits
J. Biol. Chem.
279
37087-37094
2004
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Pirkov, I.; Norbeck, J.; Gustafsson, L.; Albers, E.
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway
FEBS J.
275
4111-4120
2008
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Tamura, H.; Saito, Y.; Ashida, H.; Inoue, T.; Kai, Y.; Yokota, A.; Matsumura, H.
Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: implications for catalytic mechanism
Protein Sci.
17
126-135
2008
Bacillus subtilis (O31662), Bacillus subtilis
Manually annotated by BRENDA team
Kabuyama, Y.; Litman, E.S.; Templeton, P.D.; Metzner, S.I.; Witze, E.S.; Argast, G.M.; Langer, S.J.; Polvinen, K.; Shellman, Y.; Chan, D.; Shabb, J.B.; Fitzpatrick, J.E.; Resing, K.A.; Sousa, M.C.; Ahn, N.G.
A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme
Mol. Cell. Proteomics
8
2308-2320
2009
Homo sapiens
Manually annotated by BRENDA team
Templeton, P.D.; Litman, E.S.; Metzner, S.I.; Ahn, N.G.; Sousa, M.C.
Structure of mediator of RhoA-dependent invasion (MRDI) explains its dual function as a metabolic enzyme and a mediator of cell invasion
Biochemistry
52
5675-5684
2013
Bacillus subtilis, Homo sapiens (Q9BV20), Homo sapiens
Manually annotated by BRENDA team
Mary, C.; Duek, P.; Salleron, L.; Tienz, P.; Bumann, D.; Bairoch, A.; Lane, L.
Functional identification of APIP as human mtnB, a key enzyme in the methionine salvage pathway
PLoS ONE
7
e52877
2012
Homo sapiens
Manually annotated by BRENDA team
Gogoi, P.; Srivastava, A.; Jayaprakash, P.; Jeyakanthan, J.; Kanaujia, S.P.
In silico analysis suggests that PH0702 and PH0208 encode for methylthioribose-1-phosphate isomerase and ribose-1,5-bisphosphate isomerase, respectively, rather than aIF2Bbeta and aIF2Bdelta
Gene
575
118-126
2016
Pyrococcus horikoshii (O58433), Pyrococcus horikoshii, Pyrococcus horikoshii DSM 12428 (O58433)
Manually annotated by BRENDA team
Ikeda, Y.; Isogai, A.; Moriyoshi, Y.; Kanda, R.; Iwashita, K.; Fujii, T.
Construction of sake yeast with low production of dimethyl trisulfide precursor by a self-cloning method
J. Biosci. Bioeng.
125
419-424
2018
Saccharomyces cerevisiae, Saccharomyces cerevisiae K901
Manually annotated by BRENDA team
Saito, Y.; Ashida, H.; Kojima, C.; Tamura, H.; Matsumura, H.; Kai, Y.; Yokota, A.
Enzymatic characterization of 5-methylthioribose 1-phosphate isomerase from Bacillus subtilis
Biosci. Biotechnol. Biochem.
71
2021-2028
2007
Bacillus subtilis (O31662), Bacillus subtilis, Bacillus subtilis 168 (O31662)
Manually annotated by BRENDA team
Gogoi, P.; Mordina, P.; Kanaujia, S.P.
Structural insights into the catalytic mechanism of 5-methylthioribose 1-phosphate isomerase
J. Struct. Biol.
205
67-77
2019
Pyrococcus horikoshii (O58433)
Manually annotated by BRENDA team
Tamura, H.; Saito, Y.; Ashida, H.; Inoue, T.; Kai, Y.; Yokota, A.; Matsumura, H.
Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis implications for catalytic mechanism
Protein Sci.
17
126-135
2008
Bacillus subtilis (O31662), Bacillus subtilis, Bacillus subtilis 168 (O31662)
Manually annotated by BRENDA team