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5.2.1.5: linoleate isomerase

This is an abbreviated version!
For detailed information about linoleate isomerase, go to the full flat file.

Word Map on EC 5.2.1.5

Reaction

9-cis,12-cis-octadecadienoate
=
9-cis,11-trans-octadecadienoate

Synonyms

C12 isomerase, FG02668.1, Isomerase, linoleate, IV39_GL000089, LA isomerase, LA-I, LAI, LAI12, Linoleate DELTA12-cis,DELTA11-trans isomerase, linoleic acid DELTA12-cis,DELTA11-trans-isomerase, Linoleic acid isomerase, PAI

ECTree

     5 Isomerases
         5.2 cis-trans-Isomerases
             5.2.1 cis-trans Isomerases (only sub-subclass identified to date)
                5.2.1.5 linoleate isomerase

Activating Compound

Activating Compound on EC 5.2.1.5 - linoleate isomerase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
125% activity at 3 mM
8-hydroxyquinoline
-
118% activity at 3 mM
alpha-alpha'-bipyridyl
-
125% activity at 3 mM
FAD
-
the addition of 5 mM NADH plus FAD to the reaction mixture with dialyzed high molecular fraction of the soluble fraction restores activity to 101%
K2MoO4
-
422% activity at 5 mM, in the presence of o-phenanthroline
K2WO4
-
149% activity at 5 mM, in the presence of o-phenanthroline
Na2MnO4
-
427% activity at 5 mM, in the presence of o-phenanthroline
Na2WO4
-
157% activity at 5 mM, in the presence of o-phenanthroline
Na3VO4
-
264% activity at 5 mM, in the presence of o-phenanthroline
NADH
-
the addition of 5 mM NADH plus FAD to the reaction mixture with dialyzed high molecular fraction of the soluble fraction restores activity to 101%
NADPH
-
the addition of 5 mM NADPH to the reaction mixture with dialyzed high molecular fraction of the soluble fraction restores activity to 98%
NaVO3
-
209% activity at 5 mM, in the presence of o-phenanthroline
additional information
-
no effects by DTT, ATP, ADP, NAD+, NADH, NADPH or CoA
-