5.1.3.2: UDP-glucose 4-epimerase

This is an abbreviated version!
For detailed information about UDP-glucose 4-epimerase, go to the full flat file.

Reaction

Synonyms

4-Epimerase, 6xHis-rGalE, ABD1_580, An14g03820, AtUGE1, AtUGE2, AtUGE3, AtUGE4, AtUGE5, CaGAL10, CapD, epimerase Ab-WbjB, Epimerase, uridine diphosphoglucose, fnlA, GAL10, Gal10p, Galactowaldenase, GalE, galE-1, galE-2, galE1, GalESp1, GalESp2, GNE, GNE2, H3634, HvUGE1, HvUGE2, HvUGE3, MdUGE1, More, OsUGE-1, OsUGE1, PsUGE1, Rdh1, rGalE, Rv3634c, TbGalE, TM0509, TMGalE, UDP-D-galactose 4-epimerase, UDP-D-glucose/UDP-D-galactose 4-epimerase, UDP-Gal 4-epimerase, UDP-Gal/Glc 4-epimerase, UDP-galactose 4'-epimerase, UDP-galactose 4-epimerase, UDP-galactose-4'-epimerase, UDP-galactose-4-epimerase, UDP-Glc 4-epimerase, UDP-Glc(NAc) 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-GlcNAc/Glc 4-epimerase, UDP-glucose 4'-epimerase, UDP-glucose 4-epimerase, UDP-glucose 4-epimerase 1, UDP-glucose 4-epimerase 4, UDP-glucose epimerase, UDP-glucose-4-epimerase, UDP-glucose/-galactose 4-epimerase, UDP-hexose 4-epimerase, UDP-N-acetyl-glucosamine 4,6-dehydratase, UDP-sugar 4-epimerase, UDP-Xyl 4-epimerase, UDP-xylose 4-epimerase, UDPG-4-epimerase, UDPgalactose 4-epimerase, UGE, UGE-1, UGE1, UGE1:GUS, Uge1p, UGE2, UGE3, UGE3:GUS, UGE4, UGE5, UgeA, Uridine diphosphate galactose 4-epimerase, Uridine diphosphate glucose 4-epimerase, uridine diphosphate-galactose-4'-epimerase, Uridine diphospho-galactose-4-epimerase, Uridine diphosphogalactose-4-epimerase, Uridine diphosphoglucose 4-epimerase, Uridine diphosphoglucose epimerase, uridine-diphospho-glucose 4-epimerase, WbjB

ECTree

     5 Isomerases

         5.1 Racemases and epimerases

             5.1.3 Acting on carbohydrates and derivatives

                5.1.3.2 UDP-glucose 4-epimerase

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Results	in table
17	Activating Compound
50920	AA Sequence
6	Application
1	CAS Registry Number
54	Cloned(Commentary)
49	Cofactor
13	Crystallization (Commentary)
154	Disease/ Diagnostics
9	Expression
120	General Information
6	General Stability
13	IC50 Value
101	Inhibitors
39	kcat/KM [mM/s]
6	Ki Value [mM]
115	KM Value [mM]
15	Localization
19	Metals/Ions
75	Molecular Weight [Da]
84	Natural Substrates/ Products (Substrates)
3	Organic Solvent Stability
185	Organism
13	Pathway
77	PDB ID
37	pH Optimum
17	pH Range
5	pH Stability
3	pI Value
108	Protein Variants
49	Purification (Commentary)
15	Reaction
14	Reaction Type
160	Reference
4	Renatured (Commentary)
49	Source Tissue
36	Specific Activity [micromol/min/mg]
6	Storage Stability
245	Substrates and Products (Substrate)
75	Subunits
303	Synonyms
1	Systematic Name
26	Temperature Optimum [°C]
5	Temperature Range [°C]
32	Temperature Stability [°C]
79	Turnover Number [1/s]

pH Range

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pH Range on EC 5.1.3.2 - UDP-glucose 4-epimerase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

3 - 10

Aeromonas hydrophila

-

-

672430

5 - 10

2 entries

5 - 7

Arabidopsis thaliana

-

MES buffer

674580

6 - 10.5

Arabidopsis thaliana

-

about 65% of maximal activity at pH 6 and 10.5

2338

6 - 8

Thermotoga maritima

Q9WYX9

over 95% of maximal activity within this range

746915

6 - 9

3 entries

6.4 - 9.6

Escherichia coli

-

6.4: 68% loss of maximal activity, 9.6: 79% of maximal activity

2327

6.5 - 9.5

Arabidopsis thaliana

-

Tris/HCl buffer

674580

6.6 - 9.2

Galdieria sulphuraria

-

about 50% of maximal activity at pH 6.6 and 9.2

2339

6.7 - 8.1

Saccharomyces cerevisiae

-

6.7: 91% of maximal activity, 8.1: 88% of maximal activity

2309

7 - 9

Escherichia coli

-

-

672093

7 - 9.7

Bifidobacterium bifidum

-

7: about 50% of maximal activity, 9.7: about 40% of maximal activity

2315

7.6 - 9.5

Vicia faba

-

7.6: about 25% of maximal activity, 9.5: maximal activity

2308

8.5 - 9

Pisum sativum

B0M3E8

maximum activity of recombinant PsUGE1

702141

5 - 10

Thermotoga maritima

Q9WYX9

over 50% of maximal activity within this range

746915

5 - 10

Thermotoga maritima

Q9WYX9

pH 5.0: about 50% of maximal activity, pH 10: about 55% of maximal activity

746915

6 - 9

Escherichia coli

-

pH-dependencies of wild-type and mutant enzymes, overview

726547

6 - 9

Marinithermus hydrothermalis

-

over 50% of maximal activity at pH 6.0 and pH 9.0

726782

6 - 9

Pyrococcus horikoshii

O73960

pH 6.0: about 80% of maximal activit, pH 9.0: about 50% of maximal activity

721850