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5.1.1.11: phenylalanine racemase (ATP-hydrolysing)

This is an abbreviated version!
For detailed information about phenylalanine racemase (ATP-hydrolysing), go to the full flat file.

Word Map on EC 5.1.1.11

Reaction

ATP
+
L-phenylalanine
+
H2O
=
AMP
+
diphosphate
+
D-phenylalanine

Synonyms

Gramicidin S synthetase I, GrsA, GS I, PheATE, Phenylalanine racemase, Phenylalanine racemase (adenosine triphosphate-hydrolyzing), Phenylalanine racemase (ATP-hydrolyzing), Racemase, phenylalanine (adenosine triphosphate-hydrolyzing)

ECTree

     5 Isomerases
         5.1 Racemases and epimerases
             5.1.1 Acting on amino acids and derivatives
                5.1.1.11 phenylalanine racemase (ATP-hydrolysing)

Natural Substrates Products

Natural Substrates Products on EC 5.1.1.11 - phenylalanine racemase (ATP-hydrolysing)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + L-phenylalanine + H2O
?
show the reaction diagram
ATP + L-phenylalanine + H2O
AMP + diphosphate + D-phenylalanine
show the reaction diagram
-
the three-domain initiation module PheATE of gramicidin S synthetase catalyzes the activation, thiolation and epimerization of L-phenylalanine, the first amino acid incorporated into the decapeptide antibiotic gramicidin S
-
?