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4.4.1.13: cysteine-S-conjugate beta-lyase

This is an abbreviated version!
For detailed information about cysteine-S-conjugate beta-lyase, go to the full flat file.

Word Map on EC 4.4.1.13

Reaction

2-aminoprop-2-enoate
=
2-iminopropanoate

Synonyms

AAR, beta-cystathionase, beta-lyase, C-DES, C-S lyase, CBL, CBL/ALR, CBS, CCBL2, Ctl1, Ctl2, cystathionine beta-lyase, cystathionine beta/gamma-lyase, cystathionine lyase, cysteine conjugate beta-lyase, cysteine conjugate. beta.-lyase, cysteine lyase, cysteine S-conjugate beta-lyase, cysteine-S-conjugate beta-lyase, cystine C-S lyase, cystine lyase, EC 4.4.1.6, EC 4.4.1.8, EcCBL, glutamine transaminase K, glutamine transaminase K/cysteine conjugate beta-lyase, GTK, Irc7p, KAT, KAT III, KYAT3, kynurenine aminotransferase, kynurenine-oxoglutarate transaminase 3, L-cystine C-S lyase, LACBS_00576, lyase, cystathionine beta-, lyase, cysteine conjugate.beta., MalY, MetC, More, Mp CBL, ORF5, osteotoxin, patB, PatB protein, Str3p, TmCBL, TTHA1620, wMelCBL

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.13 cysteine-S-conjugate beta-lyase

KM Value

KM Value on EC 4.4.1.13 - cysteine-S-conjugate beta-lyase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.5
2,4-dinitrophenyl-L-cysteine
0.013
3-hydroxy-kynurenine
-
-
0.6
beta-chloro-L-alanine
-
-
2.6
beta-chloroalanine
-
-
0.02 - 4.2
cystathionine
1
cystine
-
estimated from steady-state measurements
5.3
D-Cys
-
-
1 - 1.4
DL-homocysteine
0.4
kynurenine
-
-
0.04 - 15
L-cystathionine
0.29 - 11.5
L-cysteine
0.0812 - 5.4
L-cystine
0.033 - 3.6
L-djenkolate
4.5
L-homolanthionine
-
-
0.83
L-meso-lanthionine
-
-
32.8 - 34.2
L-methionine
0.35
L-selenocystathionine
-
-
2
L-selenodjenkolate
-
-
0.104
Lanthionine
-
-
6.5
O-methyl-DL-serine
-
-
0.008
pyridoxal phosphate
-
-
8.4
S-(1,1,2,2-tetrafluoroethyl)-L-cysteine
-
23°C, pH 7.4
1.36 - 1.39
S-(1,2-dichlorovinyl)-L-cysteine
0.47
S-(2-aminoethyl)-L-Cys
-
-
0.01 - 1.66
S-(2-benzothiazolyl)-L-cysteine
1.02 - 1.78
S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine
0.7
S-(p-bromophenyl)-L-cysteine
-
-
0.1 - 0.33
S-1,2-dichlorovinyl-L-cysteine
0.08
S-2,4-dinitrophenyl-L-cysteine
-
-
0.73
S-Benzyl-L-cysteine
-
-
0.67
S-methyl-L-Cys
-
-
2.3 - 5.3
S-methyl-L-cysteine
2.3
S-methyl-L-cysteine sulfoxide
-
-
4.6
Se-(methyl)-L-selenocysteine
-
-
additional information
additional information
-