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4.4.1.11: methionine gamma-lyase

This is an abbreviated version!
For detailed information about methionine gamma-lyase, go to the full flat file.

Word Map on EC 4.4.1.11

Reaction

L-methionine
+
H2O
=
methanethiol
+
NH3
+
2-oxobutanoate

Synonyms

CalE6, EhMGL1, EhMGL2, fer1MgL2, Fn1419, L-methionase, L-methioninase, L-methionine gamma-lyase, L-methionine gamma-lyase 1, L-methionine-alpha-deamino-gamma-mercaptomethane lyase, L-methionine-alpha-deamino-gamma-mercaptomethane-lyase, L-methionine-gamma-lyase, lyase, methionine, MdeA, MegL, METase, methioninase, methionine alpha,gamma-lyase, methionine dethiomethylase, methionine gamma-lyase, methionine lyase, methionine-gamma-lyase, MGL, MGL1, MGL2, rMETase, sav7062, TvMGL1, TvMGL2, YtjE

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.11 methionine gamma-lyase

Molecular Weight

Molecular Weight on EC 4.4.1.11 - methionine gamma-lyase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
149000
-
gel filtration
159000
160000
165000
-
sedimentation equilibrium method
167500
gel filtration
170000
171000 - 177000
172000
173000
174000
-
low-angle light-scattering method
180000
-
gel filtration
258000
-
native enzyme, gel filtration
37500
-
4 * 37500, SDS-PAGE
40000
-
x * 40000, x * 48000, disc gel electrophoresis, guanidine hydrochloride
41000
-
4 * 41000, SDS-PAGE
42000
-
4 * 42000, SDS-PAGE, gel filtration
42560
-
METase, mass spectrometry
42600
-
4 * 42600, SDS-PAGE
42630
-
METase, calculated from amino acid sequence
43000
43000 - 45000
SDS-PAGE
43100
x * 43100, calculated
43300
43500
43700
4 * 43700, SDS-PAGE, immunoblot, native and recombinant EhMGL2 form homotetramers
44000
-
4 * 44000, SDS-PAGE
44040
-
4 * 44040, His-tagged enzyme, sequence calcualtion
44080
-
4 * 44080, His-tagged enzyme, sequence calcualtion
44360
-
4 * 44360, His-tagged enzyme, sequence calcualtion
44670
calculated from amino acid sequence
45000
-
4 * 45000, SDS-PAGE
47820
-
x * 47820, calculated, x * 48000, SDS-PAGE
48000
55000
-
4 * 55000, SDS-PAGE
77510
-
DTT-treated PEG-METase, mass spectrometry
81400
gel filtration
82500
86700
-
DTT-untreated PEG-METase, calculated from amino acid sequence