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4.4.1.11: methionine gamma-lyase

This is an abbreviated version!
For detailed information about methionine gamma-lyase, go to the full flat file.

Word Map on EC 4.4.1.11

Reaction

L-methionine
+
H2O
=
methanethiol
+
NH3
+
2-oxobutanoate

Synonyms

CalE6, EhMGL1, EhMGL2, fer1MgL2, Fn1419, L-methionase, L-methioninase, L-methionine gamma-lyase, L-methionine gamma-lyase 1, L-methionine-alpha-deamino-gamma-mercaptomethane lyase, L-methionine-alpha-deamino-gamma-mercaptomethane-lyase, L-methionine-gamma-lyase, lyase, methionine, MdeA, MegL, METase, methioninase, methionine alpha,gamma-lyase, methionine dethiomethylase, methionine gamma-lyase, methionine lyase, methionine-gamma-lyase, MGL, MGL1, MGL2, rMETase, sav7062, TvMGL1, TvMGL2, YtjE

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.11 methionine gamma-lyase

Inhibitors

Inhibitors on EC 4.4.1.11 - methionine gamma-lyase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
3-Methyl-2-benzothiazolinone hydrazone
-
-
3-methyl-2-benzothiazonlinone hydrazone
-
1 mM, 23.6% residual activity
5,5'-dithiobis(2-nitrobenzoic acid)
5-5'-dithiobis-(2-nitrobenzoic acid)
aminoethyloxyvinylglycine
carbonyl reagents
-
cycloserine
-
-
DL-Penicillamine
DL-propargylglycine
glycine
HgCl2
hydroxylamine
iodacetamide
-
-
iodoacetamide
iodoacetate
iodoacetic acid
L-2-amino-4-chloro-4-pentenoate
-
complete inhibition at 5 mol per mol of tetramer enzyme
L-2-aminobutanoate
-
-
L-Cycloserine
L-norleucine
L-norvaline
-
-
L-Vinylglycine
-
microspectrophotometric measurements
myrsinoic acid B
N-ethylmaleimide
NaBH4
NaCl
-
0.4% wt/vol, 78% residual activity
p-chloromercuri-benzoic acid
p-chloromercuribenzoate
p-chloromercuribenzoic acid
-
-
Penicillamine
propargylglycine
Semicarbazide
Sodium arsenate
Achromobacter starkeyi
-
-
Sodium azide
-
-
sulfhydryl inhibitors
-
additional information
-