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4.3.2.1: argininosuccinate lyase

This is an abbreviated version!
For detailed information about argininosuccinate lyase, go to the full flat file.

Word Map on EC 4.3.2.1

Reaction

2-(Nomega-L-arginino)succinate
=
fumarate
 +
L-arginine

Synonyms

AL, ARG4, ArgH, arginine-succinate lyase, argininosuccinase, Argininosuccinate lyase, argininosuccinic acid lyase, Arginosuccinase, ASAL, ASL, delta2 crystallin, delta2-crystallin, hASL, L-argininosuccinate arginine-lyase, lyase, argininosuccinate, Rv1659

ECTree

     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.2 Amidine-lyases
                4.3.2.1 argininosuccinate lyase

Source Tissue

Source Tissue on EC 4.3.2.1 - argininosuccinate lyase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
the enzynme is overexpressed in breast cancer
Manually annotated by BRENDA team
-
present in neurones and nerve fibres in the myenteric plexus of the lower oesophagael sphincter, antrum, pylorus, ileum and colon, in the submucosal plexus of ileum and colon, in longitudinal muscle of ileum and colon, nerve bundles of circular muscles
Manually annotated by BRENDA team
-
ASL expression is time-dependently reduced in hypoxia
Manually annotated by BRENDA team
using DNA
Manually annotated by BRENDA team
-
expression of enzyme genetic variant OsASL1.1
Manually annotated by BRENDA team
-
expression of enzyme genetic variant OsASL1.1
Manually annotated by BRENDA team
-
low mRNA content
Manually annotated by BRENDA team
-
nerve fibers of smooth muscle layer
Manually annotated by BRENDA team
-
fumarate hydratase defiecient or proficient cells, the latter termed UOKpFH cells
Manually annotated by BRENDA team
additional information