4.2.3.4: 3-dehydroquinate synthase

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For detailed information about 3-dehydroquinate synthase, go to the full flat file.

Reaction

Synonyms

3-dehydroquinate synthase, 3-dehydroquinate synthetase, 3-dehydroquinic acid synthetase, 5-dehydroquinate synthase, 5-dehydroquinic acid synthetase, aroB, dehydroquinate synthase, dehydroquinate synthetase, DHQ synthase, DHQS, EC 4.6.1.3, hpDHQS, synthase, 5-dehydroquinate, Xoo1243

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.3 Acting on phosphates

                4.2.3.4 3-dehydroquinate synthase

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Results	in table
1	Activating Compound
35355	AA Sequence
4	Application
1	CAS Registry Number
20	Cloned(Commentary)
26	Cofactor
10	Crystallization (Commentary)
1	General Information
1	General Stability
3	IC50 Value
65	Inhibitors
11	kcat/KM [mM/s]
3	Ki Value [mM]
27	KM Value [mM]
1	Localization
35	Metals/Ions
47	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
81	Organism
6	Pathway
69	PDB ID
6	pH Optimum
2	pH Range
17	Purification (Commentary)
3	Reaction
10	Reaction Type
69	Reference
6	Source Tissue
34	Specific Activity [micromol/min/mg]
6	Storage Stability
42	Substrates and Products (Substrate)
15	Subunits
43	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Temperature Stability [°C]
15	Turnover Number [1/s]

KI Value

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KI Value on EC 4.2.3.4 - 3-dehydroquinate synthase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0176

7-deoxysedoheptulose

Trichormus variabilis

Q3M4V2

pH 7.5, 29°C

763080

-

0.0000008

CBP

Helicobacter pylori

P56081

contains 5 functional groups (OH, COOH and phosphate)

690739

0.236

chlorogenic acid

Providencia alcalifaciens

X6Q997

pH 7.4, 25°C

763209