4.2.1.96: 4a-hydroxytetrahydrobiopterin dehydratase

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For detailed information about 4a-hydroxytetrahydrobiopterin dehydratase, go to the full flat file.

Word Map on EC 4.2.1.96

4.2.1.96

pterins

hyperphenylalaninemias

dihydropteridine

bh4

hydroxylases

cyclohydrolase

7-biopterin

6-pyruvoyl-tetrahydropterin

vitiligo

hnf1alpha

sepiapterin

tetrahydropterins

depigmentation

gtpch

Reaction

Synonyms

4 alpha-Hydroxy-tetrahydropterin dehydratase, 4-alpha-hydroxy-tetrahydropterin dehydratase, 4-alpha-hydroxytetrahydrobiopterin dehydratase, 4a-Carbinolamine dehydratase, 4a-Hydroxytetrahydrobiopterin dehydratase, 4a-Hydroxytetrahydropterin dehydratase, carbinolamine-4a-dehydratase, cDcoH, DCoH, DCoH/PCD, DcoH2, DCoHalpha, Dehydratase, 4a-carbinolamine, Dimerization cofactor of hepatocyte nuclear factor 1-alpha, Dimerization cofactor of HNF1, Dimerization factor of HNF1/pterin-4alpha-carbinolamine dehydratase, GenBank AE000671-derived protein GI 2982796, More, P4aCD, PCD, PCD/DCoH, PCD/PhhB, PCDH, Phenylalanine hydroxylase-stimulating protein, Phenylalanine hydroxylase-stimulating protein/pterin-4alpha-carbinolamine dehydratase, PhhB, PHS, PHS/PCD, pterin 4a-carbinolamine dehydratase, Pterin carbinolamine dehydratase, Pterin-4 alpha-carbinolamine dehydratase, Pterin-4-alpha-carbinolamine dehydratase, Pterin-4a-carbinolamine dehydratase, Pterin-4a-carbinolamine dehydratase (Aquifex aeolicus gene phhB), Pterin-4a-carbinolamine dehydratase/dimerization cofactor of HNF1, Pterin-4alpha-carbinolamine dehydratase, Pterin-4alpha-carbinolamine dehydratase (PCD)/dimerization cofactor for the transcription factor HBF-1alpha, XDCoH

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.96 4a-hydroxytetrahydrobiopterin dehydratase

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Results	in table
1	Activating Compound
29794	AA Sequence
2	CAS Registry Number
17	Cloned(Commentary)
6	Crystallization (Commentary)
56	Disease/ Diagnostics
12	General Information
1	General Stability
5	Inhibitors
38	KM Value [mM]
11	Localization
1	Metals/Ions
15	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
34	Organism
6	Pathway
38	PDB ID
24	Protein Variants
11	Purification (Commentary)
4	Reaction
2	Reaction Type
34	Reference
1	Renatured (Commentary)
21	Source Tissue
4	Specific Activity [micromol/min/mg]
2	Storage Stability
38	Substrates and Products (Substrate)
16	Subunits
61	Synonyms
1	Systematic Name
10	Turnover Number [1/s]

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23 - 24

(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin

4 entries

8.6 - 10

4a(R)-hydroxy-6(S)-methyltetrahydropterin

3 entries

2.4 - 10

4a(S)-hydroxy-6(R)-methyltetrahydropterin

3 entries