4.2.1.8: mannonate dehydratase
This is an abbreviated version!
For detailed information about mannonate dehydratase, go to the full flat file.
Word Map on EC 4.2.1.8
-
4.2.1.8
-
mands
-
dehydration
-
enolase
-
d-glucuronate
-
2-keto-3-deoxy-d-gluconate
-
high-efficiency
-
cap
-
low-efficiency
-
racemase
-
2-keto-3-deoxygluconate
-
dissimilation
-
mandelate
-
barrel
- 4.2.1.8
-
mands
- dehydration
- enolase
- d-glucuronate
- 2-keto-3-deoxy-d-gluconate
-
high-efficiency
- cap
-
low-efficiency
- racemase
- 2-keto-3-deoxygluconate
-
dissimilation
- mandelate
-
barrel
Reaction
Synonyms
Altronate hydrolase, Altronic hydro-lyase, CCNA_00566, D-mannonate dehydratase, D-mannonate hydrolase, D-Mannonate hydrolyase, Dehydratase, mannonate, EcManD, ManD, mannonate dehydratase, Mannonate hydrolyase, Mannonic hydrolase, UxuA
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Reference on EC 4.2.1.8 - mannonate dehydratase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Robert-Baudouy, J.M.; Stoeber, F.R.
Purification et proprietes de la D-mannonate hydrolase d'Escherichia coli'
Biochim. Biophys. Acta
309
473-485
1973
Escherichia coli
Robert-Baudouy, J.; Jimeno-Abendano, J.; Stoeber, F.
D-Mannonate and D-altronate dehydratases of Escherichia coli K12
Methods Enzymol.
90
288-294
1982
Escherichia coli
Dreyer, J.L.
The role of iron in the activation of mannonic and altronic acid hydratases, two Fe-requiring hydro-lyases
Eur. J. Biochem.
166
623-630
1987
Escherichia coli
Farmer, J.J.; Eagon, R.G.
Aldohexuronic acid catabolism by a soil Aeromonas
J. Bacteriol.
97
97-106
1969
Aeromonas sp., Aeromonas sp. C11-2B
Ashwell, G.; Wahba, A.J.; Hickman, J.
A new pathway of uronic acid metabolism
Biochim. Biophys. Acta
30
186-187
1958
Escherichia coli
Rakus, J.F.; Fedorov, A.A.; Fedorov, E.V.; Glasner, M.E.; Vick, J.E.; Babbitt, P.C.; Almo, S.C.; Gerlt, J.A.
Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans
Biochemistry
46
12896-12908
2007
Novosphingobium aromaticivorans
Zhang, Q.; Gao, F.; Peng, H.; Cheng, H.; Liu, Y.; Tang, J.; Thompson, J.; Wei, G.; Zhang, J.; Du, Y.; Yan, J.; Gao, G.F.
Crystal structures of Streptococcus suis mannonate dehydratase (ManD) and its complex with substrate: genetic and biochemical evidence for a catalytic mechanism
J. Bacteriol.
191
5832-5837
2009
Streptococcus suis (A4VVI4), Streptococcus suis
Wichelecki, D.J.; Graff, D.C.; Al-Obaidi, N.; Almo, S.C.; Gerlt, J.A.
Identification of the In vivo Function of the High Efficiency D-Mannonate Dehydratase in Caulobacter crescentus NA1000 from the Enolase Superfamily
Biochemistry
53
4087-4089
2014
Caulobacter vibrioides (A0A0H3C643)
Qiu, X.; Tao, Y.; Zhu, Y.; Yuan, Y.; Zhang, Y.; Liu, H.; Gao, Y.; Teng, M.; Niu, L.
Structural insights into decreased enzymatic activity induced by an insert sequence in mannonate dehydratase from Gram negative bacterium
J. Struct. Biol.
180
327-334
2012
Escherichia coli (P24215), Escherichia coli
Wichelecki, D.J.; Graff, D.C.; Al-Obaidi, N.; Almo, S.C.; Gerlt, J.A.
Identification of the in vivo function of the high-efficiency D-mannonate dehydratase in Caulobacter crescentus NA1000 from the enolase superfamily
Biochemistry
53
4087-4089
2014
Caulobacter vibrioides (A0A0H3C643), Caulobacter vibrioides NA1000 (A0A0H3C643), Caulobacter vibrioides NA1000
Wichelecki, D.J.; Vendiola, J.A.; Jones, A.M.; Al-Obaidi, N.; Almo, S.C.; Gerlt, J.A.
Investigating the physiological roles of low-efficiency D-mannonate and D-gluconate dehydratases in the enolase superfamily pathways for the catabolism of L-gulonate and L-idonate
Biochemistry
53
5692-5699
2014
Chromohalobacter salexigens (Q1QT83), Chromohalobacter salexigens DSM 3043 (Q1QT83), Chromohalobacter salexigens DSM 3043
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