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4.2.1.79: 2-methylcitrate dehydratase

This is an abbreviated version!
For detailed information about 2-methylcitrate dehydratase, go to the full flat file.

Word Map on EC 4.2.1.79

Reaction

(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate
=
(Z)-but-2-ene-1,2,3-tricarboxylate
+
H2O

Synonyms

2-MC dehydratase, 2-methylcitrate dehydratase, 2-methylcitrate dehydratase 1, 2-Methylcitrate hydro-lyase, Dehydratase, 2-methylcitrate, methylcitrate dehydratase, mmgE, PrpD, SePrpD, STM0370

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.79 2-methylcitrate dehydratase

Natural Substrates Products

Natural Substrates Products on EC 4.2.1.79 - 2-methylcitrate dehydratase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate
(Z)-but-2-ene-1,2,3-tricarboxylate + H2O
show the reaction diagram
(2S,3S)-2-methylcitrate
cis-2-methylaconitate
show the reaction diagram
(2S,3S)-hydroxybutane-1,2,3-tricarboxylate
(Z)-but-2-ene-1,2,3-tricarboxylate + H2O
show the reaction diagram
enzyme performs the isomerization of (2S,3S)-methylcitrate to (2R,3S)-2-methylisocitrate together with aconitase, both enzymes are essential, overview
-
r
2-Hydroxybutane-1,2,3-tricarboxylate
(Z)-But-2-ene-1,2,3-tricarboxylate + H2O
show the reaction diagram
2-Hydroxybutane-1,2,3-tricarboxylate
?
show the reaction diagram
-
methylcitric acid cycle, propionyl-CoA oxidation
-
-
?
2-methylcitrate
2-methyl-cis-aconitate + H2O
show the reaction diagram
additional information
?
-