4.2.1.78: (S)-norcoclaurine synthase

This is an abbreviated version!
For detailed information about (S)-norcoclaurine synthase, go to the full flat file.

Word Map on EC 4.2.1.78

4.2.1.78

nanocrystals

nerve

nanoclusters

photoluminescence

nanoparticles

colloidal

fabric

semiconductor

luminescence

nanocomposites

perovskite

neuropathy

optoelectronic

halide

tunable

dope

nanostructures

excitons

as-prepared

doping

monodisperse

nanomaterials

electrocatalytic

bimetallic

sural

photocatalytic

dopants

photothermal

carpal

photovoltaic

ulnar

light-emitting

alloy

nanocapsules

bioimaging

polyneuropathy

core-shell

photoelectron

nanocubes

photocatalysts

hrtem

electrocatalysts

solvothermal

ultrasmall

heterostructures

tunability

synthesis

vacancy

radiative

as-synthesized

photocurrent

Reaction

Synonyms

(S)-norcoclaurine synthase, (S)-Norlaudanosoline synthase, AmNCS1, AmNCS2, CCHNCS2, CjNCS1, CjPR10A, CsNCS, More, NCS, NCS1, NCS2, NDONCS3, norcoclaurine synthase, PbNCS, PR10A, PSONCS1, PSONCS2, S-norcoclaurine synthase, Synthase, (S)-norlaudanosoline, TFLNCSDELTA25, TfNCS

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.78 (S)-norcoclaurine synthase

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Results	in table
2	Activating Compound
27	AA Sequence
7	Application
2	CAS Registry Number
19	Cloned(Commentary)
4	Crystallization (Commentary)
1	Expression
18	General Information
4	Inhibitors
1	Ki Value [mM]
22	KM Value [mM]
4	Localization
2	Metals/Ions
4	Molecular Weight [Da]
35	Natural Substrates/ Products (Substrates)
46	Organism
6	Pathway
12	PDB ID
8	pH Optimum
3	pH Range
4	pI Value
7	Protein Variants
13	Purification (Commentary)
6	Reaction
3	Reaction Type
44	Reference
38	Source Tissue
2	Specific Activity [micromol/min/mg]
4	Storage Stability
89	Substrates and Products (Substrate)
4	Subunits
50	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
2	Temperature Range [°C]
1	Temperature Stability [°C]
15	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 4.2.1.78 - (S)-norcoclaurine synthase

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4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]

The reaction makes a six-membered ring by forming a bond between C-6 of the 3,4-dihydroxyphenyl group of the dopamine and C-1 of the aldehyde in the imine formed between the substrates. The product is the precursor of the benzylisoquinoline alkaloids in plants. The enzyme, formerly known as (S)-norlaudanosoline synthase, will also catalyse the reaction of 4-(2-aminoethyl)benzene-1,2-diol + (3,4-dihydroxyphenyl)acetaldehyde to form (S)-norlaudanosoline, but this alkaloid has not been found to occur in plants.