4.2.1.78: (S)-norcoclaurine synthase
This is an abbreviated version!
For detailed information about (S)-norcoclaurine synthase, go to the full flat file.
Word Map on EC 4.2.1.78
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4.2.1.78
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nanocrystals
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nerve
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nanoclusters
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photoluminescence
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nanoparticles
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colloidal
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fabric
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semiconductor
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luminescence
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nanocomposites
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perovskite
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neuropathy
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optoelectronic
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halide
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tunable
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dope
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nanostructures
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excitons
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as-prepared
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doping
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monodisperse
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nanomaterials
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electrocatalytic
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bimetallic
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sural
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photocatalytic
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dopants
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photothermal
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carpal
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photovoltaic
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ulnar
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light-emitting
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alloy
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nanocapsules
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bioimaging
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polyneuropathy
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core-shell
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photoelectron
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nanocubes
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photocatalysts
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hrtem
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electrocatalysts
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solvothermal
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ultrasmall
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heterostructures
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tunability
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synthesis
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vacancy
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radiative
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as-synthesized
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photocurrent
- 4.2.1.78
-
nanocrystals
- nerve
-
nanoclusters
-
photoluminescence
- nanoparticles
-
colloidal
-
fabric
-
semiconductor
-
luminescence
-
nanocomposites
-
perovskite
- neuropathy
-
optoelectronic
- halide
-
tunable
-
dope
-
nanostructures
-
excitons
-
as-prepared
-
doping
-
monodisperse
-
nanomaterials
-
electrocatalytic
-
bimetallic
-
sural
-
photocatalytic
-
dopants
-
photothermal
-
carpal
-
photovoltaic
-
ulnar
-
light-emitting
-
alloy
-
nanocapsules
-
bioimaging
- polyneuropathy
-
core-shell
-
photoelectron
-
nanocubes
-
photocatalysts
-
hrtem
-
electrocatalysts
-
solvothermal
-
ultrasmall
-
heterostructures
-
tunability
- synthesis
-
vacancy
-
radiative
-
as-synthesized
-
photocurrent
Reaction
Synonyms
(S)-norcoclaurine synthase, (S)-Norlaudanosoline synthase, AmNCS1, AmNCS2, CCHNCS2, CjNCS1, CjPR10A, CsNCS, More, NCS, NCS1, NCS2, NDONCS3, norcoclaurine synthase, PbNCS, PR10A, PSONCS1, PSONCS2, S-norcoclaurine synthase, Synthase, (S)-norlaudanosoline, TFLNCSDELTA25, TfNCS
ECTree
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Application
Application on EC 4.2.1.78 - (S)-norcoclaurine synthase
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synthesis
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development of an efficient, stereoselective, green synthesis of (S)-norcoclaurine, i.e. higenamine, using the recombinant (S)-norcoclaurine synthase enzyme, starting from the cheap tyrosine and dopamine substrates in a one-pot, two step process, overview. The optimized process affords enantiomerically pure (S)-norcoclaurine (93%) in a yield higher than 80% and allows good recovery of the enzyme for recycling, by a green Pictet-Spengler synthesis
synthesis
the enzyme can catalyse the Pictet-Spengler reaction between dopamine and unactivated ketones, thus facilitating the facile biocatalytic generation of 1,1'-disubstituted tetrahydroisoquinolines. Variants of the enzyme showing improved conversions are identified and used to synthesize novel chiral 1,10-disubstituted and spiro-tetrahydroisoquinolines
synthesis
the enzyme can serve as a tool to synthesize unnatural, optically active tetrahydroisoquinolines. The enzyme is a promising catalyst that functions to stereoselectively produce various 1-substituted-1,2,3,4-tetrahydroisoquinolines
synthesis
the enzyme has also shown great potential as a biocatalyst for the formation of chiral isoquinolines
synthesis
the enzyme is a highly suitable catalyst for the Pictet-Spengler reaction
synthesis
the enzyme is a highly suitable catalyst for the Pictet-Spengler reaction
synthesis
the enzyme is a highly suitable catalyst for the Pictet-Spengler reaction. The enzyme is successfully immobilized on various carriers whereby EziG3 proves to be the best suited for biotransformations