4.2.1.54: lactoyl-CoA dehydratase

This is an abbreviated version!
For detailed information about lactoyl-CoA dehydratase, go to the full flat file.

Reaction

Synonyms

(R)-lactyl-CoA dehydratase, acrylyl coenzyme A hydratase, dehydratase, lactoyl-coenzyme A, lactoyl coenzyme A dehydratase, lactoyl-CoA dehydratase subunit alpha, lactyl CoA dehydratase, lactyl-CoA dehydrase, lactyl-CoA dehydratase, lactyl-coenzyme A dehydrase, LCD, lcdA

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.54 lactoyl-CoA dehydratase

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Results	in table
5	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
3	Cofactor
1	General Stability
2	Metals/Ions
3	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
35	Organism
1	Oxidation Stability
7	Pathway
2	pH Optimum
2	Purification (Commentary)
3	Reaction
2	Reaction Type
29	Reference
5	Specific Activity [micromol/min/mg]
2	Storage Stability
34	Substrates and Products (Substrate)
1	Subunits
52	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 4.2.1.54 - lactoyl-CoA dehydratase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(2R)-2-hydroxybutyryl-CoA

crotonyl-CoA + H2O

Anaerotignum propionicum

-

stereospecific elimination of the 3Si hydrogen

33930

-

33930

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

23 entries

acrylyl-CoA + H2O

lactoyl-CoA

4 entries

crotonoyl-CoA + H2O

2-hydroxybutyryl-CoA

2 entries

lactoyl-CoA

acrylyl-CoA

2 entries

lactoyl-CoA + H2O

?

2 entries

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Anaerotignum propionicum

-

-

718680

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Anaerotignum propionicum

G3KIM4

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Anaerotignum propionicum DSM 1682

-

-

718680

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Anaerotignum propionicum DSM 1682

G3KIM4

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

butyrate-producing bacterium SS3/4

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridioides difficile

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridioides difficile 630

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium botulinum

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium botulinum A2

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium botulinum C Eklund

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium novyi

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium novyi NT

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium sp.

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium sp. M62/1

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Clostridium sp. MSTE9 (cluster XIVb)

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Coprococcus catus

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Coprococcus catus GD/7

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Enterocloster asparagiformis

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Enterocloster asparagiformis DSM 15981

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Megasphaera elsdenii

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

Megasphaera elsdenii LC1 DSM 20460T

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

[Clostridium] symbiosum

-

-

729862

-

-

?

(R)-lactoyl-CoA

acryloyl-CoA + H2O

[Clostridium] symbiosum WAL-14163

-

-

729862

-

-

?

acrylyl-CoA + H2O

lactoyl-CoA

Anaerotignum propionicum

-

-

33931

-

33931

?

acrylyl-CoA + H2O

lactoyl-CoA

Anaerotignum propionicum

-

-

33929

-

33929

r

acrylyl-CoA + H2O

lactoyl-CoA

Megasphaera elsdenii

-

-

33926

-

33926

?

acrylyl-CoA + H2O

lactoyl-CoA

Megasphaera elsdenii

-

-

33927

-

33927

?

crotonoyl-CoA + H2O

2-hydroxybutyryl-CoA

Anaerotignum propionicum

-

-

33929

-

-

r

crotonoyl-CoA + H2O

2-hydroxybutyryl-CoA

Megasphaera elsdenii

-

-

33926

-

-

?

lactoyl-CoA

acrylyl-CoA

Anaerotignum propionicum

-

-

33929

-

33929

r

lactoyl-CoA

acrylyl-CoA

Anaerotignum propionicum

-

-

33931

-

33931

r

lactoyl-CoA + H2O

?

Anaerotignum propionicum

-

-

33930

-

-

?

lactoyl-CoA + H2O

?

Megasphaera elsdenii

-

enzyme in the pathway of propionate formation

33927

-

-

?