4.2.1.47: GDP-mannose 4,6-dehydratase

This is an abbreviated version!
For detailed information about GDP-mannose 4,6-dehydratase, go to the full flat file.

Word Map on EC 4.2.1.47

4.2.1.47

alginate

fucosylation

gdp-l-fucose

mucoid

l-fucose

gdp-4-keto-6-deoxy-d-mannose

gdp-mannuronic

gdp-d-rhamnose

phosphomannomutase

fucosyltransferase

gdp-4-keto-6-deoxymannose

d-rhamnose

synthesis

biotechnology

Reaction

Synonyms

ATCV-1GMD, bceN, Dm-gmd, GDP-alpha-D-mannose 4,6-dehydratase, GDP-D-mannose 4,6-dehydratase, GDP-D-mannose 4-oxido-6-reductase, GDP-D-mannose dehydratase, GDP-D-mannose-4,6-dehydratase, GDP-mannose 4, 6-dehydratase, GDP-mannose 4,6 dehydratase, GDP-mannose 4,6-dehydratase, GDP-mannose dehydratase, GDP-mannose dehydrogenase, GDP-mannose-4,6-dehydratase, GMD, GMDS, guanosine 5'-diphosphate-D-mannose 4,6-dehydratase, Guanosine 5'-diphosphate-D-mannose oxidoreductase, Guanosine diphosphomannose 4,6-dehydratase, Guanosine diphosphomannose oxidoreductase, L-GMD, M-GMD, MUR1, ORF13.7, PBCV-1 GMD, S-GMD

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.47 GDP-mannose 4,6-dehydratase

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Results	in table
6	Activating Compound
28462	AA Sequence
3	Application
1	CAS Registry Number
22	Cloned(Commentary)
18	Cofactor
4	Crystallization (Commentary)
33	Disease/ Diagnostics
9	General Information
3	General Stability
34	Inhibitors
2	kcat/KM [mM/s]
6	Ki Value [mM]
17	KM Value [mM]
1	Localization
7	Metals/Ions
21	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
57	Organism
1	Oxidation Stability
14	Pathway
66	PDB ID
9	pH Optimum
4	pH Range
4	Protein Variants
19	Purification (Commentary)
3	Reaction
1	Reaction Type
54	Reference
17	Source Tissue
9	Specific Activity [micromol/min/mg]
5	Storage Stability
73	Substrates and Products (Substrate)
16	Subunits
57	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
9	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 4.2.1.47 - GDP-mannose 4,6-dehydratase

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dithiothreitol

Mortierella alpina

D3JU53

enhances GMD activity by 2.3fold

702081

DTT

Mortierella alpina

D3JU53

enhances GMD activity by 2.3fold

NADPH

Pyridine nucleotides

additional information

Pseudomonas aeruginosa

specific activity activity of GDP-mannose dehydrogense increases with dissolved oxygen tension of up to 25% of air saturation and maintains the maximal value up to at least 70% of air saturation

665895