4.2.1.46: dTDP-glucose 4,6-dehydratase

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For detailed information about dTDP-glucose 4,6-dehydratase, go to the full flat file.

Reaction

Synonyms

DesIV, dTDP-D-glucose 4,6-dehydratase, dTDP-D-glucose oxidoreductase, dTDP-glucose-4,6-dehydratase, dTGD, RmbB, rml-2, RmlB, TDP-D-glucose 4,6-dehydratase, TDP-glucose oxidoreductase, TDPDH, Thymidine diphosphate D-glucose oxidoreductase, thymidine diphosphate-glucose 4,6-dehydratase, Thymidine diphospho-D-glucose 4,6-dehydratase, Thymidine diphosphoglucose oxidoreductase, UDP-D-glucose 4,6-dehydratase, Ugd

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.1 Hydro-lyases

                4.2.1.46 dTDP-glucose 4,6-dehydratase

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Results	in table
1	Activating Compound
36877	AA Sequence
7	Application
1	CAS Registry Number
11	Cloned(Commentary)
25	Cofactor
4	Crystallization (Commentary)
6	General Information
2	General Stability
2	IC50 Value
37	Inhibitors
4	Ki Value [mM]
48	KM Value [mM]
4	Metals/Ions
22	Molecular Weight [Da]
64	Natural Substrates/ Products (Substrates)
83	Organism
31	Pathway
35	PDB ID
14	pH Optimum
2	pH Range
1	pH Stability
35	Protein Variants
21	Purification (Commentary)
1	Reaction
1	Reaction Type
82	Reference
13	Specific Activity [micromol/min/mg]
7	Storage Stability
105	Substrates and Products (Substrate)
13	Subunits
111	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
51	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 4.2.1.46 - dTDP-glucose 4,6-dehydratase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

10% loss of activity during storage at 0¦C for 1 week

Escherichia coli

-

5721

50% loss of activity during storage at -20¦C or -80¦C for less than 1 week

Saccharopolyspora erythraea

-

5712

60% loss of activity during storage in 0.025 M potassium phosphate or 0.025 M Tris-HCl at 0¦C for 24 hours, stable for several days at 0¦C and buffer concentrations of 0.25 M or 20% glycerol or 34% sucrose

Streptomyces rimosus

-

5713

stable at -12¦C, 10% loss of activity during storage at room temperature for 1 h, loss of activity upon repeated freezing and thawing

Escherichia coli

-

5719

stable for several months at -15¦C

Escherichia coli

-

5720

stable for several weeks at -20�C

2 entries

stable for several weeks at -20�C

Escherichia coli

-

5721

stable for several weeks at -20�C

Streptomyces rimosus

-

5713