4.2.1.42: galactarate dehydratase

This is an abbreviated version!
For detailed information about galactarate dehydratase, go to the full flat file.

Word Map on EC 4.2.1.42

4.2.1.42

enolase

dehydration

racemase

mandelate

departure

agrobacterium

alpha-proton

aldolase

dyad

beta-strands

glycerate

d-galacturonate

analysis

seventh

epimerization

typhimurium

semialdehyde

Reaction

Synonyms

A9CG74, Dehydratase, galactarate, Galactarate dehydrase, galactarate dehydratase, galactarate dehydratase III, GalcD, GalrD, GalrD-III, L-talarate/galactarate dehydratase, m-galactarate dehydratase, STM3697

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.1 Hydro-lyases

4.2.1.42 galactarate dehydratase

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Results	in table
3991	AA Sequence
4	Application
1	CAS Registry Number
6	Cloned(Commentary)
3	Crystallization (Commentary)
2	General Information
1	General Stability
6	Inhibitors
9	kcat/KM [mM/s]
2	Ki Value [mM]
10	KM Value [mM]
5	Metals/Ions
4	Natural Substrates/ Products (Substrates)
32	Organism
6	Pathway
6	PDB ID
3	pH Optimum
1	pH Range
11	Protein Variants
6	Purification (Commentary)
1	Reaction
1	Reaction Type
11	Reference
1	Specific Activity [micromol/min/mg]
20	Substrates and Products (Substrate)
18	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
9	Turnover Number [1/s]

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Reference on EC 4.2.1.42 - galactarate dehydratase

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5083

Hubbard, B.K.; Koch, M.; Palmer, D.R.J.; Babbitt, P.C.; Gerlt, J.A.

Evolution of enzymatic activities in the enolase superfamily: characterization of the (D)-glucarate/galactarate catabolic pathway in Escherichia coli

Biochemistry

14369-14375

1998

Escherichia coli, Escherichia coli CR63MA

9772162

5701

Blumenthal, H.J.; Jepson, T.

Galactarate dehydrase

Methods Enzymol.

665-669

1966

Escherichia coli, Escherichia coli CR63MA

678325

Yew, W.S.; Fedorov, A.A.; Fedorov, E.V.; Almo, S.C.; Gerlt, J.A.

Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2

Biochemistry

9564-9577

2007

Salmonella enterica subsp. enterica serovar Typhimurium (Q8ZL58), Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (Q8ZL58), Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720 (Q8ZL58)

17649980

702265

Rakus, J.F.; Kalyanaraman, C.; Fedorov, A.A.; Fedorov, E.V.; Mills-Groninger, F.P.; Toro, R.; Bonanno, J.; Bain, K.; Sauder, J.M.; Burley, S.K.; Almo, S.C.; Jacobson, M.P.; Gerlt, J.A.

Computation-facilitated assignment of the function in the enolase superfamily: a regiochemically distinct galactarate dehydratase from Oceanobacillus iheyensis

Biochemistry

11546-11558

2009

Oceanobacillus iheyensis

19883118

729259

Groninger-Poe, F.P.; Bouvier, J.T.; Vetting, M.W.; Kalyanaraman, C.; Kumar, R.; Almo, S.C.; Jacobson, M.P.; Gerlt, J.A.

Evolution of enzymatic activities in the enolase superfamily: galactarate dehydratase III from Agrobacterium tumefaciens C58

Biochemistry

4192-4203

2014

Agrobacterium tumefaciens, Agrobacterium tumefaciens C58 / ATCC 33970

24926996

746735

Easton, N.M.; Aboushawareb, S.A.E.; Bearne, S.L.

A continuous assay for L-talarate/galactarate dehydratase using circular dichroism

Anal. Biochem.

544

80-86

2018

Salmonella enterica subsp. enterica serovar Typhimurium (Q8ZL58), Salmonella enterica subsp. enterica serovar Typhimurium

29248502