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4.2.1.36: homoaconitate hydratase

This is an abbreviated version!
For detailed information about homoaconitate hydratase, go to the full flat file.

Word Map on EC 4.2.1.36

Reaction

(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate
=
(Z)-but-1-ene-1,2,4-tricarboxylate
+
H2O

Synonyms

2-hydroxy-3-carboxyadipate hydro-lyase, cis-Homoaconitase, HACN, HACNMj, Homoaconitase, Homoaconitate hydratase, Hydratase, homoaconitate, leuC, LYS4, lysF, MJ0499, MJ1271

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.36 homoaconitate hydratase

KM Value

KM Value on EC 4.2.1.36 - homoaconitate hydratase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.5
(R)-homocitrate
-
in 50 mM Tris-HCl (pH 8.5), 50 mM KCl, 5 mM MgCl2, 20 mM dithiothreitol, at 20°C
0.022 - 0.46
(Z)-but-1-ene-1,2,4-tricarboxylate
0.036 - 0.66
(Z)-hex-1-ene-1,2,6-tricarboxylate
0.03 - 1.6
(Z)-pent-1-ene-1,2,5-tricarboxylate
1.1
2-hydroxy-3-carboxyadipate
-
-