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4.2.1.34: (S)-2-methylmalate dehydratase

This is an abbreviated version!
For detailed information about (S)-2-methylmalate dehydratase, go to the full flat file.

Word Map on EC 4.2.1.34

Reaction

(S)-2-methylmalate
=
2-methylfumarate
+
H2O

Synonyms

(+)-Citramalic hydro-lyase, Bxe_A3136, Dehydratase, citramalate, FumA, fumarase A, fumarase/mesaconase, FumD, Hydratase, mesaconate, Mesaconase, Mesaconase, mesaconate, mesaconase/fumarase, Mesaconate hydratase

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.34 (S)-2-methylmalate dehydratase

pH Stability

pH Stability on EC 4.2.1.34 - (S)-2-methylmalate dehydratase

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7 - 11
-
component I is stable
5668
7 - 8
-
4°C, 48 h, about 20% loss of activity of component II
5668
7.5
-
at pH 7.5 or below component II partially dissociates into species with molecular weights of about 165000 Da, 82000 Da, and 37000 Da. At pH 9.0 these species reassociate to form active component II of about the original MW. The observed species may represent a monomer, dimer, tetramer and octamer of a single subunit
5666