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4.2.1.3: aconitate hydratase

This is an abbreviated version!
For detailed information about aconitate hydratase, go to the full flat file.

Word Map on EC 4.2.1.3

Reaction

citrate
=
cis-aconitate
+
H2O

Synonyms

Acn, AcnA, AcnA3, AcnB, ACO, Aco1, Aco2, Aco3, ACO4, acon, aconitase, aconitase 2, aconitase A, aconitase B, aconitase/2-methylaconitate hydratase, Aconitate hydratase, AH, c-acon, c-aconitase, CAA, cis-aconitase, citB, citrate hydro-lyase, cytoplasmic aconitase, cytoplasmic aconitase/iron regulatory protein 1 homolog, EC 4.2.1.4, Ferritin repressor protein, hydratase, aconitate, IP210, IRE-BP, Iron regulatory protein, iron regulatory protein 1, iron regulatory-like protein, iron-regulatory protein 1, iron-responsive element binding protein, IRP, IRP-1, IRP1, mACON, Major iron-containing protein, MICP, More, PfIRPa, SPBP4H10.15

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.3 aconitate hydratase

Temperature Stability

Temperature Stability on EC 4.2.1.3 - aconitate hydratase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30
-
5 h, 50% loss of activity, isoenzyme II. 15 h, 90% loss of activity, isoenzyme I. 15 h, 75% loss of activity, isoenzyme II
45
-
complete inactivation after 20 min without fluorocitrate, stable in presence of fluorocitrate 0.05 mM, 40% loss of activity in presence of 20 mM citrate
5
-
15 h, 50% inactivation, isoenzyme I. 15 h, about 65% loss of activity, isoenzyme II
50
-
30 min, stable
60
-
10 min, complete inactivation
95
-
half-life: 14 min