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4.2.1.3: aconitate hydratase

This is an abbreviated version!
For detailed information about aconitate hydratase, go to the full flat file.

Word Map on EC 4.2.1.3

Reaction

citrate
=
cis-aconitate
 +
H2O

Synonyms

Acn, AcnA, AcnA3, AcnB, ACO, Aco1, Aco2, Aco3, ACO4, acon, aconitase, aconitase 2, aconitase A, aconitase B, aconitase/2-methylaconitate hydratase, Aconitate hydratase, AH, c-acon, c-aconitase, CAA, cis-aconitase, citB, citrate hydro-lyase, cytoplasmic aconitase, cytoplasmic aconitase/iron regulatory protein 1 homolog, EC 4.2.1.4, Ferritin repressor protein, hydratase, aconitate, IP210, IRE-BP, Iron regulatory protein, iron regulatory protein 1, iron regulatory-like protein, iron-regulatory protein 1, iron-responsive element binding protein, IRP, IRP-1, IRP1, mACON, Major iron-containing protein, MICP, More, PfIRPa, SPBP4H10.15

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.3 aconitate hydratase

Specific Activity

Specific Activity on EC 4.2.1.3 - aconitate hydratase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.011 - 0.06
-
aconitate hydratase in blood serum of control rats and rats subjected to myocardial ischemia and treatment with lipoic acid, overview
0.068 - 0.198
-
aconitate hydratase in myocardium of control rats and rats subjected to myocardial ischemia and treatment with lipoic acid, overview
0.206
-
dehydration of citrate to cis-aconitate, pH 8.0, 30°C
0.266
-
dehydration of isocitrate to cis-aconitate, pH 8.0, 30°C
0.433
-
reverse reaction, hydration of citrate or isocitrate, pH 8.0, 30°C
1.11
-
cytoplasmic isoenzyme
11.1
-
cytosolic enzyme
118
-
pH 8.0, 25°C
2.126
Cucurbita sp.
-
isoenzyme Aco II
2.214
Cucurbita sp.
-
isoenzyme Aco I
21.4
-
-
3.4
-
mitochondrial isoenzyme
3.95
-
isoform Aco4, pH 8.0, 25°C
4.06
-
isoform Aco1, pH 8.0, 25°C
6.13
-
mitochondrial enzyme
additional information