4.1.99.1: tryptophanase

This is an abbreviated version!
For detailed information about tryptophanase, go to the full flat file.

Word Map on EC 4.1.99.1

Reaction

L-tryptophan
+
H2O
=
indole
+
pyruvate
+
NH3

Synonyms

tryptophan indole-lyase, Tpase, L-tryptophanase, tryptophanase, TNase, L-tryptophan indole-lyase, Trpase, TIL, TnaA, tryptophan-indole lyase, tryptophan indole lyase, VcTrpase, tna2, tnaA2, tryptophanase 2

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.99 Other carbon-carbon lyases
                4.1.99.1 tryptophanase

Turnover Number

Turnover Number on EC 4.1.99.1 - tryptophanase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.22 - 5.6
beta-(benzimidazol-1-yl)-L-alanine
3 - 12.4
beta-chloro-L-Ala
0.0932
beta-chloroalanine
-
pH 7.8, 37°C, mutant enzyme Y72F
0.0303
L-Ser
-
pH 7.8, 37°C, mutant enzyme Y72F
0.24 - 42
L-Trp
0.009 - 6.8
L-tryptophan
2.2 - 44
S-(2-nitrophenyl)-L-cysteine
1.1 - 5.2
S-benzyl-L-Cys
0.346
S-Benzyl-L-cysteine
recombinant His-tagged wild-type enzyme, pH 7.8, 37°C
0.00046
S-benzylcysteine
-
pH 7.8, 37°C, mutant enzyme Y72F
0.4 - 6
S-ethyl-L-Cys
0.035 - 6
S-ethyl-L-cysteine
0.0051 - 5
S-methyl-L-Cys
0.2 - 0.5
S-methyl-L-cysteine
0.423
S-o-nitrophenyl-L-Cys
-
pH 7.8, 37°C, mutant enzyme Y72F
0.00004
Trp
-
pH 7.8, 37°C, mutant enzyme Y72F