4.1.3.1: isocitrate lyase

This is an abbreviated version!
For detailed information about isocitrate lyase, go to the full flat file.

Word Map on EC 4.1.3.1

4.1.3.1

interstrand

malate

lens

eyes

collamer

postoperative

intraocular

crosslinks

refract

preoperative

phakic

acuity

fanconi

anemia

posterior

spherical

uncorrected

myopic

vault

fork

diopter

corneal

astigmatism

glyoxysomal

fancd2

pupil

lymphocytopenia

translesion

logmar

itaconate

anaplerotic

monoubiquitination

psoralens

monoadducts

gaba-induced

vision-threatening

pupillary

incisions

hyperopic

keratomileusis

subcapsular

lasik

microbodies

biomicroscopy

drug development

snellen

medicine

as-oct

best-corrected

sn-glycerol-3-phosphate

spectacle

molecular biology

gelatinosa

Reaction

isocitrate

=

succinate

+

glyoxylate

Synonyms

AceA, acuD, citrate lyase, D-threo-isocitrate: glyoxylate lyase, EgGCE, FPICL1, ICL, ICL1, ICL2, isocitrase, isocitratase, isocitrate lyase, isocitrate lyase 1, isocitrate lyase 2, isocitric lyase, isocitritase, lyase, isocitrate, MtbIcl, PDP, petal death protein, SSO1333, threo-DS-Isocitrate glyoxylate-lyase

ECTree

4.1 Carbon-carbon lyases

4.1.3 Oxo-acid-lyases

4.1.3.1 isocitrate lyase

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Results	in table
42	Activating Compound
16957	AA Sequence
15	Application
1	CAS Registry Number
45	Cloned(Commentary)
8	Crystallization (Commentary)
19	Expression
61	General Information
4	General Stability
120	IC50 Value
523	Inhibitors
5	kcat/KM [mM/s]
24	Ki Value [mM]
130	KM Value [mM]
18	Localization
95	Metals/Ions
114	Molecular Weight [Da]
98	Natural Substrates/ Products (Substrates)
822	Organism
3	Oxidation Stability
7	Pathway
118	PDB ID
56	pH Optimum
8	pH Range
4	pH Stability
3	pI Value
4	Posttranslational Modification
63	Protein Variants
72	Purification (Commentary)
4	Reaction
2	Reaction Type
210	Reference
59	Source Tissue
80	Specific Activity [micromol/min/mg]
31	Storage Stability
235	Substrates and Products (Substrate)
72	Subunits
208	Synonyms
1	Systematic Name
27	Temperature Optimum [°C]
4	Temperature Range [°C]
37	Temperature Stability [°C]
31	Turnover Number [1/s]

Organism

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Organism on EC 4.1.3.1 - isocitrate lyase

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Acinetobacter calcoaceticus

-

-

-

Manually annotated by BRENDA team

Amaranthus caudatus

cultivar Kinelskiy 254

-

-

Manually annotated by BRENDA team

Aspergillus fumigatus

show

Aspergillus fumigatus ATCC 46645

strain ATCC46645

-

-

Manually annotated by BRENDA team

Aspergillus nidulans

-

33141, 33142, 33143, 653939, 705567

-

-

Manually annotated by BRENDA team

Aspergillus niger

-

-

-

Manually annotated by BRENDA team

Aspergillus niger N402

-

-

-

Manually annotated by BRENDA team

Azotobacter vinelandii

show

Azotobacter vinelandii IAM1078

gene icl

UniProt

Manually annotated by BRENDA team

Bacillus sp. (in: Bacteria)

thermophilic

-

-

Manually annotated by BRENDA team

Bradyrhizobium japonicum

-

-

-

Manually annotated by BRENDA team

Bradyrhizobium japonicum USDA110

-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Burkholderia pseudomallei

strains 1026b and DD503

-

-

Manually annotated by BRENDA team

Candida albicans

show

Candida albicans ATCC 10231

-

-

-

Manually annotated by BRENDA team

Candida brassicae

-

-

-

Manually annotated by BRENDA team

Candida tropicalis

-

33119, 33120, 33144

-

-

Manually annotated by BRENDA team

Capsicum annuum

cultivar World Beater

-

-

Manually annotated by BRENDA team

Chlamydomonas reinhardtii

-

-

-

Manually annotated by BRENDA team

Citrullus lanatus subsp. vulgaris

-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Colletotrichum lagenaria

-

-

-

Manually annotated by BRENDA team

Colwellia maris

show

Colwellia psychrerythraea

-

UniProt

Manually annotated by BRENDA team

Colwellia psychrerythraea NRC 1004

-

UniProt

Manually annotated by BRENDA team

Corynebacterium glutamicum

gene aceA

-

-

Manually annotated by BRENDA team

Corynebacterium glutamicum ATCC 31831

gene aceA

-

-

Manually annotated by BRENDA team

Cryptococcus neoformans

-

-

-

Manually annotated by BRENDA team

Cucumis sativus

cucumber

33132, 33138, 33150

-

-

Manually annotated by BRENDA team

Debaryomyces hansenii

Y7426

-

-

Manually annotated by BRENDA team

Debaryomyces hansenii Y7426

Y7426

-

-

Manually annotated by BRENDA team

Dianthus caryophyllus

-

SwissProt

Manually annotated by BRENDA team

Escherichia coli

show

Escherichia coli K-12 W3110

-

-

-

Manually annotated by BRENDA team

Euglena gracilis

show

Euglena gracilis SM-ZK

SM-ZK

Swissprot

Manually annotated by BRENDA team

Fomitopsis palustris

show

Fomitopsis palustris TYP-6137

formerly named Tyromyces palustris

EMBL

Manually annotated by BRENDA team

Fusarium graminearum

-

UniProt

Manually annotated by BRENDA team

Geobacillus stearothermophilus

-

-

-

Manually annotated by BRENDA team

Gloeothece citriformis PCC 7424

-

-

-

Manually annotated by BRENDA team

show

Gossypium hirsutum

cotton

Uniprot

Manually annotated by BRENDA team

Haloferax volcanii

-

-

-

Manually annotated by BRENDA team

Haloferax volcanii DSM 3757

-

-

-

Manually annotated by BRENDA team

Helianthus annuus

sunflower

-

-

Manually annotated by BRENDA team

Hyphomicrobium methylovorum

-

-

-

Manually annotated by BRENDA team

Kluyveromyces lactis

Klicl1 deletion mutant

-

-

Manually annotated by BRENDA team

Leptosphaeria maculans

-

-

-

Manually annotated by BRENDA team

Linum usitatissimum

-

-

-

Manually annotated by BRENDA team

Lupinus sp.

-

33130, 33131, 33138

-

-

Manually annotated by BRENDA team

Mycobacterium avium

-

-

-

Manually annotated by BRENDA team

Mycobacterium avium My 330/88

-

-

-

Manually annotated by BRENDA team

Mycobacterium kansasii

-

-

-

Manually annotated by BRENDA team

Mycobacterium kansasii 6509/96

-

-

-

Manually annotated by BRENDA team

Mycobacterium kansasii My 235/80

-

-

-

Manually annotated by BRENDA team

Mycobacterium tuberculosis

show

Mycobacterium tuberculosis H37R

-

-

-

Manually annotated by BRENDA team

Mycobacterium tuberculosis H37Rv

show

Mycobacterium tuberculosis My 331/88

-

-

-

Manually annotated by BRENDA team

Mycobacterium tuberculosis variant bovis

-

-

-

Manually annotated by BRENDA team

Mycolicibacterium smegmatis

1-2c

-

-

Manually annotated by BRENDA team

Mycolicibacterium smegmatis 1-2c

1-2c

-

-

Manually annotated by BRENDA team

Neurospora crassa

-

33137, 33143, 747240

-

-

Manually annotated by BRENDA team

ssp. indica cv Guangluai

-

-

Manually annotated by BRENDA team

Paecilomyces variotii

-

-

-

Manually annotated by BRENDA team

Papilio machaon

-

-

-

Manually annotated by BRENDA team

Paracoccidioides brasiliensis

show

Phycomyces blakesleeanus

-

-

-

Manually annotated by BRENDA team

Pinus densiflora

-

-

-

Manually annotated by BRENDA team

-

33122, 33123, 33138, 650574, 653514

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Pseudomonas aeruginosa

show

Pseudomonas fluorescens

-

-

-

Manually annotated by BRENDA team

Pseudomonas fluorescens 13525

-

-

-

Manually annotated by BRENDA team

Pseudomonas putida

wild-type: KT2442, mutant: KT217, poly(3-hydroxyalkanoate)-overproducing mutant in which aceA gene is knocked out

-

-

Manually annotated by BRENDA team

Puccinia striiformis f. sp. tritici

-

-

-

Manually annotated by BRENDA team

Puccinia striiformis f. sp. tritici CYR32

-

-

-

Manually annotated by BRENDA team

Pyricularia grisea

-

678657, 680310, 705567, 747240

-

-

Manually annotated by BRENDA team

Pyricularia grisea Guy 11

-

-

-

Manually annotated by BRENDA team

Pyricularia oryzae

-

UniProt

Manually annotated by BRENDA team

Rattus norvegicus

-

-

-

Manually annotated by BRENDA team

Rhizobium tropici

-

-

-

Manually annotated by BRENDA team

Rhodococcus equi

show

Rhodopseudomonas sp.

-

-

-

Manually annotated by BRENDA team

Ricinus communis

show

Saccharolobus solfataricus

-

UniProt

Manually annotated by BRENDA team

Saccharolobus solfataricus P2

-

UniProt

Manually annotated by BRENDA team

Salmonella enterica

serovar typhimurium

-

-

Manually annotated by BRENDA team

Salmonella enterica subsp. enterica serovar Typhimurium

-

-

-

Manually annotated by BRENDA team

Sinorhizobium meliloti

-

680497, 705567, 746757

-

-

Manually annotated by BRENDA team

Sinorhizobium meliloti Rm5000

-

-

-

Manually annotated by BRENDA team

Solanum lycopersicum

cultivar Moneymaker

-

-

Manually annotated by BRENDA team

Streptomyces clavuligerus

NRRL 3585

SwissProt

Manually annotated by BRENDA team

Streptomyces clavuligerus NRRL 3585

NRRL 3585

SwissProt

Manually annotated by BRENDA team

Sulfolobus acidocaldarius

strain DSM 639

-

-

Manually annotated by BRENDA team

Talaromyces marneffei

show

Talaromyces marneffei CBS 119456

CBS 119456

-

-

Manually annotated by BRENDA team

isolate ATCC 95640

-

-

Manually annotated by BRENDA team

Turbatrix aceti

-

-

-

Manually annotated by BRENDA team

Vogesella indigofera

-

33126, 33127, 33128, 33137, 747240

-

-

Manually annotated by BRENDA team

Yarrowia lipolytica

-

-

-

Manually annotated by BRENDA team

Yersinia enterocolitica

-

-

-

Manually annotated by BRENDA team

Yersinia pestis

-

-

-

Manually annotated by BRENDA team

Yersinia pseudotuberculosis

-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

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Release 2023.1 (January 2023)