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4.1.3.1: isocitrate lyase

This is an abbreviated version!
For detailed information about isocitrate lyase, go to the full flat file.

Word Map on EC 4.1.3.1

Reaction

isocitrate
=
succinate
 +
glyoxylate

Synonyms

AceA, acuD, citrate lyase, D-threo-isocitrate: glyoxylate lyase, EgGCE, FPICL1, ICL, ICL1, ICL2, isocitrase, isocitratase, isocitrate lyase, isocitrate lyase 1, isocitrate lyase 2, isocitric lyase, isocitritase, lyase, isocitrate, MtbIcl, PDP, petal death protein, SSO1333, threo-DS-Isocitrate glyoxylate-lyase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.1 isocitrate lyase

KM Value

KM Value on EC 4.1.3.1 - isocitrate lyase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.1
(2R)-2-ethyl malate
pH 7.5, 25°C
0.29
(2R)-2-methyl malate
pH 7.5, 25°C
0.45 - 0.53
(2R)-ethyl-(3S)-methyl malate
8
(2R)-isobutyl-(3S)-methyl malate
pH 7.5, 25°C
0.098
(2R)-propyl-(3S)-methyl malate
pH 7.5, 25°C
0.104
(2R,3R:2S,3S)-2-methyl-isocitrate
pH 7.5, 25°C
0.026 - 0.029
(2R,3S)-2,3-dimethyl malate
0.042
(2R,3S)-isocitrate
pH 7.5, 25°C
0.069 - 0.718
(2R,3S:2S,3R)-2-methyl-isocitrate
0.025
acetyl-CoA
pH 8.0, 30°C
1.16
D-isocitrate
-
pH 7.0, 40°C
0.015 - 1.7
DL-isocitrate
0.018 - 0.25
Ds-isocitrate
0.014 - 1.3
glyoxylate
0.0157 - 7.6
isocitrate
0.092
Mg2+
-
pH 7
0.13
oxalacetate
pH 7.5, 25°C
0.044 - 6
succinate
0.145 - 1.3
threo D-(s)-isocitrate
1.142 - 2.031
threo-DL-Isocitrate
0.008 - 0.3
threo-Ds-isocitrate
additional information
additional information
-