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4.1.3.1: isocitrate lyase

This is an abbreviated version!
For detailed information about isocitrate lyase, go to the full flat file.

Word Map on EC 4.1.3.1

Reaction

isocitrate
=
succinate
+
glyoxylate

Synonyms

AceA, acuD, citrate lyase, D-threo-isocitrate: glyoxylate lyase, EgGCE, FPICL1, ICL, ICL1, ICL2, isocitrase, isocitratase, isocitrate lyase, isocitrate lyase 1, isocitrate lyase 2, isocitric lyase, isocitritase, lyase, isocitrate, MtbIcl, PDP, petal death protein, SSO1333, threo-DS-Isocitrate glyoxylate-lyase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.1 isocitrate lyase

Activating Compound

Activating Compound on EC 4.1.3.1 - isocitrate lyase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
acetate
-
activity of the ICL promoter is significantly upregulated during growth on acetate
acetyl-CoA
cysteine
dithioerythritol
Candida brassicae
-
increase of activity
dithiothreitol
glutaredoxin 1
-
reactivation of GSSG-treated ICL in the presence of glutaredoxin 1 within 20 min
-
glutathione
L-cysteine
-
45% increase of activity at 1 mM
Na2S2O4
Lupinus sp.
-
increase of activity
Reducing agents
Lupinus sp.
-
increase of activity
-
sulfhydryl compounds
thioglycolate
Lupinus sp.
-
increase of activity
thiol compounds
additional information
-