4.1.2.32: trimethylamine-oxide aldolase

This is an abbreviated version!
For detailed information about trimethylamine-oxide aldolase, go to the full flat file.

Reaction

Synonyms

TMAO demethylase, TMAOase, Trimethylamine N-oxide aldolase, Trimethylamine N-oxide demethylase, Trimethylamine N-oxide formaldehyde-lyase, trimethylamine oxide aldolase, trimethylamine-N-oxide demethylase

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.2 Aldehyde-lyases

                4.1.2.32 trimethylamine-oxide aldolase

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Results	in table
9	Activating Compound
2	AA Sequence
1	CAS Registry Number
6	Cofactor
4	General Stability
19	Inhibitors
6	KM Value [mM]
2	Localization
7	Metals/Ions
4	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
32	Organism
4	Pathway
4	pH Optimum
4	pH Range
4	Purification (Commentary)
2	Reaction
1	Reaction Type
32	Reference
17	Source Tissue
3	Specific Activity [micromol/min/mg]
25	Substrates and Products (Substrate)
2	Subunits
24	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Stability [°C]

Specific Activity

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Specific Activity on EC 4.1.2.32 - trimethylamine-oxide aldolase

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.19

Dosidicus gigas

-

cell extract, at 50°C

680290

159

Dosidicus gigas

-

after 839fold purification, at 50°C

680290

additional information

Aminobacter aminovorans

-

specific activity is much higher in ultrasonic extracts of Pseudomonas aminovorans grown on methylamine than in cells grown on trimethylamine and trimethylamine N-oxide, low activity in trimethylamine and trimethylamine N-oxide grown cells is due to the presence of an inactivating factor. The inactivating factor is absent from methylamine-grown cells

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