4.1.2.27: sphinganine-1-phosphate aldolase

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For detailed information about sphinganine-1-phosphate aldolase, go to the full flat file.

Word Map on EC 4.1.2.27

4.1.2.27

sphingolipids

ceramide

sphingoid

egress

lymphopenia

dihydrosphingosine-1-phosphate

medicine

fingolimod

s1p-degrading

sphks

4-deoxypyridoxine

steroid-resistant

analysis

lyase-deficient

s1p-dependent

spinster

s1p-induced

Reaction

Synonyms

aldolase, dihydrosphingosine 1-phosphate, Dihydrosphingosine 1-phosphate aldolase, dihydrosphingosine phosphate lyase, Dpl1, Dpl1p, LegS2, S-1-P-lyase, S1P lyase, S1P-lyase, S1PL, S1PL2021, Sgpl1, sphinganine 1-phosphate lyase, sphinganine-1-phosphate aldolase, sphinganine-1-phosphate lyase, sphinganine-1-phosphate-alkanal-lyase, sphingosine 1-phosphate lyase, sphingosine phosphate lyase, sphingosine-1-phosphate lyase, sphingosine-phosphate lyase, SPL, SPL1

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.2 Aldehyde-lyases

4.1.2.27 sphinganine-1-phosphate aldolase

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Results	in table
114	AA Sequence
16	Application
1	CAS Registry Number
17	Cloned(Commentary)
49	Cofactor
4	Crystallization (Commentary)
466	Disease/ Diagnostics
7	Expression
42	General Information
2	General Stability
66	IC50 Value
224	Inhibitors
1	kcat/KM [mM/s]
14	Ki Value [mM]
13	KM Value [mM]
53	Localization
2	Metals/Ions
12	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
118	Organism
5	Pathway
16	PDB ID
2	pH Optimum
4	Posttranslational Modification
32	Protein Variants
6	Purification (Commentary)
18	Reaction
2	Reaction Type
115	Reference
192	Source Tissue
8	Specific Activity [micromol/min/mg]
4	Storage Stability
141	Substrates and Products (Substrate)
17	Subunits
152	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 4.1.2.27 - sphinganine-1-phosphate aldolase

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55000

Symbiobacterium thermophilum

x * 55000, SDS-PAGE

59480

61000 - 65000

63000

x * 63000, SDS-PAGE

63480

calculated from amino acid sequence

652518

63490

Homo sapiens

O95470

calculated from amino acid sequence

63500

63710

calculation from cDNA nucleotide sequence

5122

65520

Saccharomyces cerevisiae

calculation from sequence of genomic DNA

5121