4.1.2.21: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
This is an abbreviated version!
For detailed information about 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, go to the full flat file.
Reaction
Synonyms
2-dehydro-3-deoxy-6-phosphogalactonate aldolase, 2-dehydro-3-deoxyphosphogalactonate aldolase, 2-keto-3-deoxy-6-phosphogalactonate aldolase, 2-keto-3-deoxy-6-phosphogalactonic aldolase, 2-keto-3-deoxygalactonate-6-phosphate aldolase, 2-oxo-3-deoxy-6-phosphogalactonate aldolase, 2-oxo-3-deoxygalactonate 6-phosphate aldolase, 6-phospho-2-dehydro-3-deoxygalactonate aldolase, 6-Phospho-2-keto-3-deoxygalactonate aldolase, aldolase, phospho-2-keto-3-deoxygalactonate, DgoA, KDPGal, KDPGal aldolase, Phospho-2-keto-3-deoxygalactonic aldolase
ECTree
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Engineering
Engineering on EC 4.1.2.21 - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
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F33I/D58N/Q72H/A75V/V85A/V154F
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higher activity compared to the wild type enzyme
V154T
the mutant shows reduced activity compared to the wild type enzyme
additional information
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mutant NR8.276-2 exhibits a 60fold improvement in the ratio kcat/KM relative to that of the wild type enzyme