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4.1.2.13: fructose-bisphosphate aldolase

This is an abbreviated version!
For detailed information about fructose-bisphosphate aldolase, go to the full flat file.

Word Map on EC 4.1.2.13

Reaction

D-fructose 1,6-bisphosphate
=
glycerone phosphate
 +
D-glyceraldehyde 3-phosphate

Synonyms

1,6-Diphosphofructose aldolase, 37 kDa major allergen, 41 kDa antigen, ALD, ALDC, aldoA, Aldob, aldolase, aldolase A, aldolase B, aldolase C, aldolase, fructose diphosphate, ALDP, bifunctional fructose-1,6-bisphosphate aldolase/phosphatase, Brain-type aldolase, Ca-FBA-II, CE1, CE2, class I Fba, class I fructose 1,6-bisphosphate aldolase, class I fructose bisphosphate aldolase, class I fructose-1,6-bisphosphate aldolase, class I muscle fructose bis-phosphate aldolase, class II aldolase, class II FBA, class II FBP aldolase, class II fructose 1,6-bisphosphate aldolase, class II fructose bisphosphate aldolase, class II fructose-1,6-bisphosphate aldolase, class IIa fructose 1,6-bisphosphate aldolase, class IIb fructose 1,6-bisphosphate aldolase, ClassII FBP-aldolase, CoFBA1, CoFBA2, CoFBA3, CoFBA4, D-fructose-1,6-bisphosphate aldolase, D-fructose-1,6-bisphosphate D-glyceraldehyde-3-P-lyase, D-fructose-6-phosphate aldolase, Diphosphofructose aldolase, DLF, EC 4.1.2.7, F1,6-P2 aldolase, F1,6P2 aldolase, F16BP aldolase, FBA, FBA class II, FBA-II, Fba1, Fba1p, Fba2, FBA7, FbaA, FbaB, FbaC, FBAld, FbaP, FBP aldolase, FBP aldolase/phosphatase, FBP-aldolase, FBPA, FBPA I, FBPA-1, FBPA/P, FDP aldolase, FPA, Fru-1,6-P2 aldolase, Fru-P2A, Fructoaldolase, fructose 1,6 bisphosphate aldolase, fructose 1,6-bisphosphatase/aldolase, Fructose 1,6-bisphosphate aldolase, fructose 1,6-bisphosphate aldolase/phosphatase, Fructose 1,6-diphosphate aldolase, Fructose 1-monophosphate aldolase, Fructose 1-phosphate aldolase, fructose bis-phosphate aldolase, Fructose bisphosphate aldolase, Fructose diphosphate aldolase, fructose-1,6-biphosphate aldolase, fructose-1,6-bisphosphate (FBP) aldolase/phosphatase, fructose-1,6-bisphosphate aldolase, fructose-1,6-bisphosphate aldolase A, fructose-1,6-bisphosphate aldolase B, fructose-1,6-bisphosphate aldolase class II, fructose-1,6-bisphosphate aldolase/phosphatase, fructose-1,6-bisphosphate muscle aldolase, Fructose-1,6-bisphosphate triosephosphate-lyase, fructose-bisphosphate aldolase, fructose-bisphosphate aldolase A, FSA, fuculose aldolase, heat-induced protein 44, HIP44, IgE-binding allergen, ketose 1-phosphate aldolase, Leishmania aldolase, Liver-type aldolase, MGA3_01355, MJ0400-His6, More, MtFBA, Muscle-type aldolase, Ov-fba-1, OvFBPA-1, Pcal_0111, Phosphofructoaldolase, SMALDO, SSO0286, STK_03180, TgALD1, Tneu_0133, TnFBPAP, Tt-FBPA, zerebrin II, zymohexase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.13 fructose-bisphosphate aldolase

Specific Activity

Specific Activity on EC 4.1.2.13 - fructose-bisphosphate aldolase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.01
-
substrate: D-fructose 1,6-bisphosphate, 50°C, pH not specified in the publication, enzyme from starch-grown cells
0.044
-
pH not specified in the publication, 37°C, activity in undialyzed cell extracts
0.123
-
after 1fold purification, at 25°C
0.13
N334K mutant, D-fructose 1-phosphate as substrate
0.28
N334K mutant, D-fructose 1,6-bisphosphate as substrate
0.3
-
-
0.38
W147R mutant, D-fructose 1-phosphate as substrate
0.58
L256P mutant, D-fructose 1-phosphate as substrate
0.64
W147R mutant, D-fructose 1,6-bisphosphate as substrate
0.81
L256P mutant, D-fructose 1,6-bisphosphate as substrate
0.86
Q354E mutant, D-fructose 1,6-bisphosphate as substrate
0.88
Q354E mutant, D-fructose 1-phosphate as substrate
0.94
wild-type enzyme, D-fructose 1-phosphate as substrate
0.97
wild-type enzyme, D-fructose 1,6-bisphosphate as substrate
1.32
purified recombinant enzyme, substrate D-fructose 1,6-bisphosphate, pH 8.0, 55°C
11.5
-
crude cell extract, at 30°C
11.7
-
A2C2 isoenzyme
11.8
-
A1C3 isoenzyme
12.3
-
A3C1 isoenzyme
13
-
A4 isoenzyme
13.2
-
strain 168, vegetative cell
15.7
mutant enzyme E206K
17.27
-
liver enzyme
18.5
-
recombinat muscle-type enzyme
2.8
-
pH 7.5, 37°C
20
-
class I aldolase
22
-
class II aldolase
22.3
wild-type enzyme
22.8
-
pH 7.2, 25°C
25.5
-
-
26.7
-
splitting of fructose 1,6-bisphosphate
3.2
-
enzyme form I
32.3
-
strain PCI 219, spore
34.85
purified native-rMtFBA
35.05
purified C-His-rMtFBA
38.4
-
pH 7.5, 37°C
4.8
-
enzyme form II
5.3
-
strain 168, spore
5.92
-
muscle-type enzyme
6.1
mutant enzyme G346S
6.4
-
-
7.01
-
recombinant non-muscle-type enzyme
7.18
-
cytosolic enzyme
7.77
-
class II aldolase
7.8
-
chloroplastic enzyme
70.3
-
after 6.1fold purification, at 30°C
8
-
A4 isoenzyme
8.62
-
class I aldolase
8.85
-
strain PCI 219, vegetative cell
additional information