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4.1.2.13: fructose-bisphosphate aldolase

This is an abbreviated version!
For detailed information about fructose-bisphosphate aldolase, go to the full flat file.

Word Map on EC 4.1.2.13

Reaction

D-fructose 1,6-bisphosphate
=
glycerone phosphate
 +
D-glyceraldehyde 3-phosphate

Synonyms

1,6-Diphosphofructose aldolase, 37 kDa major allergen, 41 kDa antigen, ALD, ALDC, aldoA, Aldob, aldolase, aldolase A, aldolase B, aldolase C, aldolase, fructose diphosphate, ALDP, bifunctional fructose-1,6-bisphosphate aldolase/phosphatase, Brain-type aldolase, Ca-FBA-II, CE1, CE2, class I Fba, class I fructose 1,6-bisphosphate aldolase, class I fructose bisphosphate aldolase, class I fructose-1,6-bisphosphate aldolase, class I muscle fructose bis-phosphate aldolase, class II aldolase, class II FBA, class II FBP aldolase, class II fructose 1,6-bisphosphate aldolase, class II fructose bisphosphate aldolase, class II fructose-1,6-bisphosphate aldolase, class IIa fructose 1,6-bisphosphate aldolase, class IIb fructose 1,6-bisphosphate aldolase, ClassII FBP-aldolase, CoFBA1, CoFBA2, CoFBA3, CoFBA4, D-fructose-1,6-bisphosphate aldolase, D-fructose-1,6-bisphosphate D-glyceraldehyde-3-P-lyase, D-fructose-6-phosphate aldolase, Diphosphofructose aldolase, DLF, EC 4.1.2.7, F1,6-P2 aldolase, F1,6P2 aldolase, F16BP aldolase, FBA, FBA class II, FBA-II, Fba1, Fba1p, Fba2, FBA7, FbaA, FbaB, FbaC, FBAld, FbaP, FBP aldolase, FBP aldolase/phosphatase, FBP-aldolase, FBPA, FBPA I, FBPA-1, FBPA/P, FDP aldolase, FPA, Fru-1,6-P2 aldolase, Fru-P2A, Fructoaldolase, fructose 1,6 bisphosphate aldolase, fructose 1,6-bisphosphatase/aldolase, Fructose 1,6-bisphosphate aldolase, fructose 1,6-bisphosphate aldolase/phosphatase, Fructose 1,6-diphosphate aldolase, Fructose 1-monophosphate aldolase, Fructose 1-phosphate aldolase, fructose bis-phosphate aldolase, Fructose bisphosphate aldolase, Fructose diphosphate aldolase, fructose-1,6-biphosphate aldolase, fructose-1,6-bisphosphate (FBP) aldolase/phosphatase, fructose-1,6-bisphosphate aldolase, fructose-1,6-bisphosphate aldolase A, fructose-1,6-bisphosphate aldolase B, fructose-1,6-bisphosphate aldolase class II, fructose-1,6-bisphosphate aldolase/phosphatase, fructose-1,6-bisphosphate muscle aldolase, Fructose-1,6-bisphosphate triosephosphate-lyase, fructose-bisphosphate aldolase, fructose-bisphosphate aldolase A, FSA, fuculose aldolase, heat-induced protein 44, HIP44, IgE-binding allergen, ketose 1-phosphate aldolase, Leishmania aldolase, Liver-type aldolase, MGA3_01355, MJ0400-His6, More, MtFBA, Muscle-type aldolase, Ov-fba-1, OvFBPA-1, Pcal_0111, Phosphofructoaldolase, SMALDO, SSO0286, STK_03180, TgALD1, Tneu_0133, TnFBPAP, Tt-FBPA, zerebrin II, zymohexase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.13 fructose-bisphosphate aldolase

IC50 Value

IC50 Value on EC 4.1.2.13 - fructose-bisphosphate aldolase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00564 - 0.0064
(1E)-1-[(4-chlorophenyl)methylidene]-2-(4-nitrophenyl)hydrazine
0.0126
(1E)-1-[(4-fluorophenyl)methylidene]-2-(4-nitrophenyl)hydrazine
0.02
(1E)-1-[(4-methylphenyl)methylidene]-2-(4-nitrophenyl)hydrazine
0.0041
(1E)-1-[([1,1'-biphenyl]-4-yl)methylidene]-2-(4-nitrophenyl)hydrazine
0.0075
(1E)-1-[1-(4-bromophenyl)ethylidene]-2-(4-nitrophenyl)hydrazine
0.0027 - 0.00276
(2E)-1-(4-nitrophenyl)-2-[(4-nitrophenyl)methylidene]hydrazine
0.02
(2E)-1-(4-nitrophenyl)-2-[(5-nitrothiophen-2-yl)methylidene]hydrazine
0.02
(2E)-2-[2-(2-hydroxy-4-nitrophenyl)hydrazinylidene]-3-oxobutanamide
Candida albicans
at pH 7.4 and 30°C
0.026
(2E)-2-[2-(4-nitrophenyl)hydrazinylidene]-1-phenylethan-1-one
0.025
1-(4-[(E)-[2-(4-nitrophenyl)hydrazinylidene]methyl]phenyl)-1H-1,2,4-triazole
0.057 - 0.13
2-carboxy-6-(phosphonomethyl)pyridinium chloride
0.017 - 0.02
3-[2-(2-hydroxy-4-nitrophenyl)hydrazinylidene]pentane-2,4-dione
0.038
3-[2-(2-hydroxyphenyl)hydrazinylidene]pentane-2,4-dione
0.043
3-[2-(2-methyl-4-nitrophenyl)hydrazinylidene]pentane-2,4-dione
0.02
3-[2-(4-nitrophenyl)hydrazinylidene]pentane-2,4-dione
0.0094
4-[(E)-[2-(4-nitrophenyl)hydrazinylidene]methyl]benzonitrile
0.006 - 0.00643
5-bromo-3-[(E)-[2-(4-nitrophenyl)hydrazinylidene]methyl]-1H-indole
0.33 - 0.533
5-chloro-8-hydroxyquinoline
0.02
5-formyl-6-hydroxynaphthalen-2-yl dihydrogen phosphate
Trypanosoma brucei
-
15 min incubation time
0.496 - 0.5
8-hydroxyquinoline
0.227
8-hydroxyquinoline-2-carboxylic acid
Staphylococcus aureus
at pH 7.8 and 25°C
0.75
ATP
Pyrobaculum calidifontis
at pH 6.0 and 25°C
0.0569
citrate
Staphylococcus aureus
at pH 7.8 and 25°C
0.028 - 0.15
dipicolinic acid
0.008 - 0.053
EDTA