4.1.2.10: (R)-mandelonitrile lyase

This is an abbreviated version!
For detailed information about (R)-mandelonitrile lyase, go to the full flat file.

Reaction

Synonyms

(R)-(+)-Mandelonitrile lyase, (R)-HNL, (R)-HNL5, (R)-hydroxynitrile lyase, (R)-Mandelonitrile lyase, (R)-Oxynitrilase, (R)-PeHNL, (R)-selective HNL, AciX9_0562, almond oxynitrilase, APHNL, AtHNL, cupin 2 conserved barrel domain protein, cupin 2 domain-containing protein, D-alpha-hydroxynitrile lyase, D-Hydroxynitrile lyase, D-Oxynitrilase, DtHNL1, EjHNL, FAD-HNL, HNL, HNL1, HNL2, HNL4, HNL5, Hydroxynitrile lyase, hydroynitrile lyase, Lyase, mandelonitrile, mandelonitrile lyase, MDL, Mdl1, NdHNL, Oxynitrilase, PaHNL, PaHNL1, PaHNL5, PaMDL, ParsHNL, PhaMDL, PmHNL, R-HNL, R-hydroxynitrile lyase, R-selective HNL, R-selective hydroxynitrile lyase

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.2 Aldehyde-lyases

                4.1.2.10 (R)-mandelonitrile lyase

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Results	in table
2	Activating Compound
396	AA Sequence
23	Application
1	CAS Registry Number
21	Cloned(Commentary)
10	Cofactor
9	Crystallization (Commentary)
4	General Information
9	General Stability
54	Inhibitors
33	kcat/KM [mM/s]
56	KM Value [mM]
1	Localization
3	Metals/Ions
32	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
14	Organic Solvent Stability
66	Organism
5	Pathway
23	PDB ID
31	pH Optimum
10	pH Range
23	pH Stability
4	pI Value
7	Posttranslational Modification
25	Protein Variants
24	Purification (Commentary)
2	Reaction
5	Reaction Type
63	Reference
27	Source Tissue
19	Specific Activity [micromol/min/mg]
2	Storage Stability
345	Substrates and Products (Substrate)
18	Subunits
95	Synonyms
1	Systematic Name
25	Temperature Optimum [°C]
6	Temperature Range [°C]
43	Temperature Stability [°C]
38	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 4.1.2.10 - (R)-mandelonitrile lyase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

(R)-mandelonitrile

cyanide + benzaldehyde

4 entries

cyanide + benzaldehyde

(R)-mandelonitrile

2 entries

(R)-mandelonitrile

cyanide + benzaldehyde

Prunus dulcis

-

-

653797

-

-

r

(R)-mandelonitrile

cyanide + benzaldehyde

Prunus dulcis

O24243

-

706367

-

-

?

(R)-mandelonitrile

cyanide + benzaldehyde

Prunus dulcis

O24243

in a large number of plant species hydroxynitrile lyases catalyzes the decomposition of cyanohydrins in order to generate hydrogen cyanide upon tissue damage. Hydrogen cyanide serves as a deterrent against herbivores and fungi

702292

-

-

r

(R)-mandelonitrile

cyanide + benzaldehyde

Prunus serotina

P52706

in Prunus serotina Ehrh. macerates, the cyanogenic diglucoside (R)-amygdalin undergoes stepwise degradation to HCN catalyzed by amygdalin hydrolase, prunasin hydrolase, and (R)-(+)-mandelonitrile lyase

646654

-

-

?

cyanide + benzaldehyde

(R)-mandelonitrile

Prunus dulcis

-

-

691796, 703209

-

-

?

cyanide + benzaldehyde

(R)-mandelonitrile

Prunus sp.

-

-

650926

-

-

r