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4.1.2.10: (R)-mandelonitrile lyase

This is an abbreviated version!
For detailed information about (R)-mandelonitrile lyase, go to the full flat file.

Word Map on EC 4.1.2.10

Reaction

(R)-mandelonitrile
=
cyanide
 +
benzaldehyde

Synonyms

(R)-(+)-Mandelonitrile lyase, (R)-HNL, (R)-HNL5, (R)-hydroxynitrile lyase, (R)-Mandelonitrile lyase, (R)-Oxynitrilase, (R)-PeHNL, (R)-selective HNL, AciX9_0562, almond oxynitrilase, APHNL, AtHNL, cupin 2 conserved barrel domain protein, cupin 2 domain-containing protein, D-alpha-hydroxynitrile lyase, D-Hydroxynitrile lyase, D-Oxynitrilase, DtHNL1, EjHNL, FAD-HNL, HNL, HNL1, HNL2, HNL4, HNL5, Hydroxynitrile lyase, hydroynitrile lyase, Lyase, mandelonitrile, mandelonitrile lyase, MDL, Mdl1, NdHNL, Oxynitrilase, PaHNL, PaHNL1, PaHNL5, PaMDL, ParsHNL, PhaMDL, PmHNL, R-HNL, R-hydroxynitrile lyase, R-selective HNL, R-selective hydroxynitrile lyase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.2 Aldehyde-lyases
                4.1.2.10 (R)-mandelonitrile lyase

Inhibitors

Inhibitors on EC 4.1.2.10 - (R)-mandelonitrile lyase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-Iodoacetamide
1 mM, 9% residual activity; 9.0% residual activity at 1 mM
2-mercaptoethanol
AgNO3
Al3+
-
50 mM, 26% loss of activity
Ba2+
-
50 mM, 6% loss of activity
Ca2+
-
10 mM, 1% inhibition
Co2+
-
10 mM, 22% inhibition
Cs2+
-
10 mM, 11% inhibition
CuSO4
1 mM, 100% inhibition
diethyl dicarbonate
diethyldicarbonate
diisopropyl fluorophosphate
2 mM, 80% inhibition
FeCl3
1 mM, 50% inhibition
HgCl2
1 mM, 100% inhibition
iodoacetamide
2 mM, 70% inhibition
iodoacetic acid
K+
-
50 mM, 11% loss of activity
Mn2+
-
10 mM, 17% inhibition
Mn4+
-
50 mM, 39% loss of activity
NH2OH
82.7% residual activity at 1 mM
p-chloromercuribenzoic acid
58.6% residual activity at 10 mM
phenylmethylsulfonyl fluoride
Phenylmethylsulfonylfluoride
1 mM, 59% inhibition
Sn2+
-
50 mM, 14% loss of activity
W6+
-
10 mM, 5% inhibition
Zn2+
-
10 mM, 2% inhibition
additional information
-