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4.1.1.53: phenylalanine decarboxylase

This is an abbreviated version!
For detailed information about phenylalanine decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.53

Reaction

L-phenylalanine
=
Phenylethylamine
+
CO2

Synonyms

More, Aromatic L-amino acid decarboxylase, AADC, Decarboxylase, phenylalanine, L-Phenylalanine decarboxylase, PDC, PDC2, PDC1, L-tyrosine/L-phenylalanine decarboxylase, disA, phenylalanine decarboxylase 1, amino acid decarboxylase, phenylalanine decarboxylase 2

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.53 phenylalanine decarboxylase

Inhibitors

Inhibitors on EC 4.1.1.53 - phenylalanine decarboxylase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5-Aminooxymethyl-2-bromophenol
-
brocresine, 75 mg/kg body mass cause 98% inhibition of liver enzyme in vivo
5-hydroxytryptophan
-
complete inhibition at 0.001 mM
alpha-Methyl-3,4-dihydroxyphenylalanine
-
competitive
alpha-Methyl-5-hydroxyphenylalanine
-
-
alpha-Methyl-m-tyrosine
-
-
alpha-Methyltryptophan
-
-
N1-(DL-Seryl)-N2-(2,3,4)-trihydroxybenzyl hydrazine
-
50 mg/kg cause 99% inhibition of liver enzyme in vivo
p-chloromercuribenzoate
-
complete inhibition at 0.01 mM
tryptamine
Micrococcus percitreus
-
42% inhibition at 0.1% v/v