4.1.1.53: phenylalanine decarboxylase
This is an abbreviated version!
For detailed information about phenylalanine decarboxylase, go to the full flat file.
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Synonyms
AADC, amino acid decarboxylase, Aromatic L-amino acid decarboxylase, Decarboxylase, phenylalanine, disA, L-Phenylalanine decarboxylase, L-tyrosine/L-phenylalanine decarboxylase, More, PDC, PDC1, PDC2, phenylalanine decarboxylase 1, phenylalanine decarboxylase 2
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Engineering
Engineering on EC 4.1.1.53 - phenylalanine decarboxylase
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additional information
genes PDC, TDC, TAL, SHT, and THT are introduced into engineered Escherichia coli strain HP-2 to synthesize N-(p-coumaroyl) phenethylamine and N-(p-coumaroyl) tyramine, method evaluation and optimization, overview. p-Coumaric acid is synthesized from tyrosine by TAL and phenethylamine is synthesized from phenylalanine by PDC. Therefore, the intracellular concentrations of both tyrosine and phenylalanine are critical for the final yield of N-(p-coumaroyl) phenethylamine
additional information
Pseudomonas putida ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440
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genes PDC, TDC, TAL, SHT, and THT are introduced into engineered Escherichia coli strain HP-2 to synthesize N-(p-coumaroyl) phenethylamine and N-(p-coumaroyl) tyramine, method evaluation and optimization, overview. p-Coumaric acid is synthesized from tyrosine by TAL and phenethylamine is synthesized from phenylalanine by PDC. Therefore, the intracellular concentrations of both tyrosine and phenylalanine are critical for the final yield of N-(p-coumaroyl) phenethylamine
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