4.1.1.46: o-pyrocatechuate decarboxylase
This is an abbreviated version!
For detailed information about o-pyrocatechuate decarboxylase, go to the full flat file.
Word Map on EC 4.1.1.46
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4.1.1.46
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decarboxylases
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aspergillus
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non-oxidative
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niger
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rhizobium
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oxysporum
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metal-dependent
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biocatalysts
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fusarium
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oryzae
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biocatalytic
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homotetrameric
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n-ethylmaleimide
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indole
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synthesis
- 4.1.1.46
- decarboxylases
- aspergillus
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non-oxidative
- niger
- rhizobium
- oxysporum
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metal-dependent
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biocatalysts
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fusarium
- oryzae
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biocatalytic
-
homotetrameric
- n-ethylmaleimide
- indole
- synthesis
Reaction
Synonyms
2,3-DHBA decarboxylase, 2,3-Dihydroxybenzoic acid decarboxylase, Decarboxylase, o-pyrocatechuate, DHBA decarboxylase, DHBD, FOIG_04675, o-Pyrocatechuic acid carboxy-lyase
ECTree
4.1.1.46 o-pyrocatechuate decarboxylaseAdvanced search results
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Application
Application on EC 4.1.1.46 - o-pyrocatechuate decarboxylase
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APPLICATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
synthesis
synthesis
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construction of an artificial pathway for muconic acid production in Escherichia coli by connecting 2,3-dihydroxybenzoic acid biosynthesis with its degradation pathway. Overexpression of entCBA and the key enzymes in the shikimate pathway leads to the production of 900 mg/l of 2,3-dihydroxybenzoic acid. Expression of 2,3-dihydroxybenzoic acid decarboxylase coupled with catechol 1,2-dioxygenase achieves the conversion of 2,3-dihydroxybenzoic acid into muconic acid. Assembly of the total pathway results in the de novo production of muconic acid up to 480 mg/l
synthesis
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development of an artificial pathway in Escherichia coli for the biosynthesis of muconic acid. Expression of 2,3-dihydroxybenzoate decarboxylase and catechol 1,2-dioxygenase and metabolic optimization by increasing the flux from chorismate through the enterobactin biosynthesis pathway and by regulating the shikimate pathway leads to synthesis of 605.18 mg/l of muconic acid from glucose in a shaking flask culture
synthesis
Klebsiella pneumoniae CICIM B7001
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development of an artificial pathway in Escherichia coli for the biosynthesis of muconic acid. Expression of 2,3-dihydroxybenzoate decarboxylase and catechol 1,2-dioxygenase and metabolic optimization by increasing the flux from chorismate through the enterobactin biosynthesis pathway and by regulating the shikimate pathway leads to synthesis of 605.18 mg/l of muconic acid from glucose in a shaking flask culture
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