4.1.1.33: diphosphomevalonate decarboxylase

This is an abbreviated version!
For detailed information about diphosphomevalonate decarboxylase, go to the full flat file.

Reaction

Synonyms

5-Pyrophosphomevalonate decarboxylase, Decarboxylase, pyrophosphomevalonate, diphosphomevalonate decarboxylase, diphosphomevalonte decarboxylase, DMD, DPM-DC, Fjoh_1389, MDD, MDP, Mevalonate (diphospho)decarboxylase, mevalonate 5'-diphosphate decarboxylase, Mevalonate 5-diphosphate decarboxylase, mevalonate diphosphate decarboxylase, mevalonate diphospho decarboxylase, Mevalonate pyrophosphate decarboxylase, mevalonate pyrophosphate decraboxylase, Mevalonate-5-pyrophosphate decarboxylase, More, MPD, MvaD, MVD, phosphomevalonate decarboxylase, PMD, Pyrophosphomevalonate decarboxylase, Pyrophosphomevalonic acid decarboxylase, ScMDD, ScMDD1, ScMDD2, scMVD, SSO2989

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.1 Carboxy-lyases

                4.1.1.33 diphosphomevalonate decarboxylase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
3	Activating Compound
6956	AA Sequence
5	Application
1	CAS Registry Number
18	Cloned(Commentary)
10	Cofactor
11	Crystallization (Commentary)
15	Disease/ Diagnostics
6	Expression
23	General Information
3	General Stability
13	IC50 Value
60	Inhibitors
13	kcat/KM [mM/s]
21	Ki Value [mM]
81	KM Value [mM]
12	Localization
29	Metals/Ions
36	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
89	Organism
7	Pathway
83	PDB ID
7	pH Optimum
3	pH Range
1	pH Stability
4	pI Value
3	Posttranslational Modification
52	Protein Variants
17	Purification (Commentary)
10	Reaction
1	Reaction Type
81	Reference
86	Source Tissue
19	Specific Activity [micromol/min/mg]
3	Storage Stability
109	Substrates and Products (Substrate)
32	Subunits
83	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
4	Temperature Stability [°C]
30	Turnover Number [1/s]

Turnover Number

print visible entries

print all entries

Turnover Number on EC 4.1.1.33 - diphosphomevalonate decarboxylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Turnover Number Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.27

(3R)-3-cyclopropyl-3-hydroxy-5-[[hydroxy(phosphonooxy)phosphoryl]oxy]pentanoic acid

Streptococcus pneumoniae

-

-

704675

1.3

(3R)-3-ethyl-3-hydroxy-5-[[hydroxy(phosphonooxy)phosphoryl]oxy]pentanoic acid

Streptococcus pneumoniae

-

-

704675

0.018

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)-4-methylpentanoic acid

Streptococcus pneumoniae

-

-

704675

0.024

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)-5-methylhexanoic acid

Streptococcus pneumoniae

-

-

704675

0.21

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)hex-4-ynoic acid

Streptococcus pneumoniae

-

-

704675

0.39

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)hex-5-enoic acid

Streptococcus pneumoniae

-

-

704675

3.2

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)pent-4-enoic acid

Streptococcus pneumoniae

-

-

704675

1.3

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)pent-4-ynoic acid

Streptococcus pneumoniae

-

-

704675

1.14 - 40

(R)-5-diphosphomevalonate

5 entries

0.0058 - 5.9

(R,S)-5-diphosphomevalonate

2 entries

0.000115 - 18.5

5-diphosphomevalonate

12 entries

30

ATP

Bacopa monnieri

A0A0F6WBJ2

pH 8.0, temperature not specified in the publication

747950

5.6

diphosphomevalonate

Streptococcus pneumoniae

-

-

704675

1.14

(R)-5-diphosphomevalonate

Staphylococcus epidermidis

Q9FD73

mutant W153F, pH 7.0, 30°C

746911

1.8

(R)-5-diphosphomevalonate

Staphylococcus epidermidis

Q9FD73

mutant W19F, pH 7.0, 30°C

746911

5.3

(R)-5-diphosphomevalonate

Staphylococcus epidermidis

Q9FD73

wild-type, pH 7.0, 30°C

746911

8.8

(R)-5-diphosphomevalonate

Staphylococcus epidermidis

Q9FD73

mutant R193T, pH 7.0, 30°C

746911

40

(R)-5-diphosphomevalonate

Bacopa monnieri

A0A0F6WBJ2

pH 8.0, temperature not specified in the publication

747950

0.0058

(R,S)-5-diphosphomevalonate

Staphylococcus epidermidis

Q9FD73

mutant enzyme S192A, at 30°C in 100 mM HEPES-NaOH (pH 7.0)

715621

5.9

(R,S)-5-diphosphomevalonate

Staphylococcus epidermidis

Q9FD73

wild type enzyme, at 30°C in 100 mM HEPES-NaOH (pH 7.0)

715621

0.000115

5-diphosphomevalonate

Saccharomyces cerevisiae

P32377

mutant S121A, pH 7.0, 30°C

664090

0.0022

5-diphosphomevalonate

Homo sapiens

P53602

mutant enzyme R161Q, at 30°C

690629

0.15

5-diphosphomevalonate

Saccharomyces cerevisiae

P32377

mutant K18M, pH 7.0, 30°C

666848

0.2

5-diphosphomevalonate

Homo sapiens

P53602

mutant enzyme N17A, at 30°C

690629

0.61

5-diphosphomevalonate

Saccharomyces cerevisiae

P32377

mutant S120A, pH 7.0, 30°C

664090

0.65

5-diphosphomevalonate

Saccharomyces cerevisiae

P32377

mutant S155A, pH 7.0, 30°C

664090

1.68

5-diphosphomevalonate

Saccharomyces cerevisiae

P32377

mutant S153A, pH 7.0, 30°C

664090

2.1

5-diphosphomevalonate

Homo sapiens

P53602

mutant enzyme S162A, at 30°C

690629

3.35

5-diphosphomevalonate

Saccharomyces cerevisiae

P32377

mutant S36A, pH 7.0, 30°C

664090

4.5

5-diphosphomevalonate

Homo sapiens

P53602

wild type enzyme, at 30°C

690629

4.9

5-diphosphomevalonate

Saccharomyces cerevisiae

P32377

wild-type, pH 7.0, 30°C

664090, 666848

18.5

5-diphosphomevalonate

Flavobacterium johnsoniae

-

pH 7.0, 30°C

746988