4.1.1.33: diphosphomevalonate decarboxylase

This is an abbreviated version!
For detailed information about diphosphomevalonate decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.33

4.1.1.33

isoprenoids

mevalonate-5-phosphate

cholesterogenesis

6-fluoromevalonate

cholestyramine

polyisoprenoid

5-phosphomevalonate

synthesis

biofuel production

pharmacology

drug development

medicine

Reaction

Synonyms

5-Pyrophosphomevalonate decarboxylase, Decarboxylase, pyrophosphomevalonate, diphosphomevalonate decarboxylase, diphosphomevalonte decarboxylase, DMD, DPM-DC, Fjoh_1389, MDD, MDP, Mevalonate (diphospho)decarboxylase, mevalonate 5'-diphosphate decarboxylase, Mevalonate 5-diphosphate decarboxylase, mevalonate diphosphate decarboxylase, mevalonate diphospho decarboxylase, Mevalonate pyrophosphate decarboxylase, mevalonate pyrophosphate decraboxylase, Mevalonate-5-pyrophosphate decarboxylase, More, MPD, MvaD, MVD, phosphomevalonate decarboxylase, PMD, Pyrophosphomevalonate decarboxylase, Pyrophosphomevalonic acid decarboxylase, ScMDD, ScMDD1, ScMDD2, scMVD, SSO2989

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.1 Carboxy-lyases

4.1.1.33 diphosphomevalonate decarboxylase

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Results	in table
3	Activating Compound
6956	AA Sequence
5	Application
1	CAS Registry Number
18	Cloned(Commentary)
10	Cofactor
11	Crystallization (Commentary)
15	Disease/ Diagnostics
6	Expression
23	General Information
3	General Stability
13	IC50 Value
60	Inhibitors
13	kcat/KM [mM/s]
21	Ki Value [mM]
81	KM Value [mM]
12	Localization
29	Metals/Ions
36	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
89	Organism
7	Pathway
83	PDB ID
7	pH Optimum
3	pH Range
1	pH Stability
4	pI Value
3	Posttranslational Modification
52	Protein Variants
17	Purification (Commentary)
10	Reaction
1	Reaction Type
81	Reference
86	Source Tissue
19	Specific Activity [micromol/min/mg]
3	Storage Stability
109	Substrates and Products (Substrate)
32	Subunits
83	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
4	Temperature Stability [°C]
30	Turnover Number [1/s]

KM Value

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KM Value on EC 4.1.1.33 - diphosphomevalonate decarboxylase

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0.001

(3R)-3-cyclopropyl-3-hydroxy-5-[[hydroxy(phosphonooxy)phosphoryl]oxy]pentanoic acid

Streptococcus pneumoniae

704675

0.0015

(3R)-3-ethyl-3-hydroxy-5-[[hydroxy(phosphonooxy)phosphoryl]oxy]pentanoic acid

Streptococcus pneumoniae

704675

0.016

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)-4-methylpentanoic acid

Streptococcus pneumoniae

704675

0.029

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)-5-methylhexanoic acid

Streptococcus pneumoniae

704675

0.0063

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)hex-4-ynoic acid

Streptococcus pneumoniae

704675

0.0028

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)hex-5-enoic acid

Streptococcus pneumoniae

704675

0.0017

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)pent-4-enoic acid

Streptococcus pneumoniae

704675

0.0029

(3R)-3-hydroxy-3-(2-[[hydroxy(phosphonooxy)phosphoryl]oxy]ethyl)pent-4-ynoic acid

Streptococcus pneumoniae

704675

0.0093 - 1.3

(R)-5-diphosphomevalonate

5 entries

0.005 - 0.0091

(R,S)-5-diphosphomevalonate

2 entries

0.01 - 12.5

5-diphosphomevalonate

24 entries

0.00053 - 7.7

ATP

34 entries

0.47

CTP

Cymbopogon citratus

4376

0.0012

diphosphomevalonate

Streptococcus pneumoniae

704675

0.3

GTP

Cymbopogon citratus

4376

0.01

mevalonate diphosphate

Mus musculus

pH 7.2

650496