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4.1.1.31: phosphoenolpyruvate carboxylase

This is an abbreviated version!
For detailed information about phosphoenolpyruvate carboxylase, go to the full flat file.

Word Map on EC 4.1.1.31

Reaction

phosphate
+
oxaloacetate
=
phosphoenolpyruvate
 +
HCO3-

Synonyms

archaeal-type phosphoenolpyruvate carboxylase, AT1G53310, atPEPC, Atppc1, Atppc2, Atppc3, Atppc4, bacterial-type PEPC, bacterial-type phosphoenolpyruvate carboxylase, BPTC, BTPC, C4 PEPC, C4-PEPC, Carboxylase, phosphopyruvate (phosphate), Class-1 PEPC, Class-2 PEPC, CP21, CP28, CP46, CrPpc1, CrPpc2, Hvpepc3, Hvpepc4, Hvpepc5, Ljpepc1, NCgl1523, OJ1484_G09.129-1, Osppc2a, Osppc4, PEOC, PEP carboxylase, PEP-carboxylase, PEPC, PEPC(p102)kinase, PEPC1, PEPC2, PEPC3, PEPC7, PepcA, PEPCase, PEPCase1, PEPCK, PEPK, phosphoenol pyruvate carboxylase, phosphoenolpyruvate carboxykinase, Phosphoenolpyruvate carboxylase, Phosphoenolpyruvic carboxylase, photosynthetic phosphoenolpyruvate carboxylase, plant-type phosphoenolpyruvate carboxylase, PPC, PPC1, PPC2, PPC2a, PPC3, PPC4, PpcA, PpcA1, PPCK1, PPCK2, PTPC, S.minutum PEPC1, Sb02g021090, Sb04g008720, SORBI_3007G106500, SSO2256, SvPEPC

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.31 phosphoenolpyruvate carboxylase

Crystallization

Crystallization on EC 4.1.1.31 - phosphoenolpyruvate carboxylase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
hanging drop vapor diffusion method, using 1.25-1.5 M sodium malonate, pH 7.0, as precipitant
PEPC complexed with L-Asp, at 2.8 A resolution
sitting drop vapor diffusion method, crystal structure of the enzyme complexed with Mn2+, the phosphoenolpyruvate analog 3,3-dichloro-2-dihydroxyphosphinoylmethyl-2-prepenoate and an allosteric inhibitor, aspartate, determined at 2.35 A resolution
three-dimensional structure of the enzyme complexed with the allosteric inhibitor L-Asp, determined by X-ray diffraction at 2.8 A resolution
docking of compound (3-bromophenyl)-4-(3-hydroxybenzylidene)-pyrazolidine-3,5-dione into the binding sites of C3 and C4 PepC
molecular modeling of structure
hanging-drop vapour-diffusion method with PEG 8000 as precipitant at pH 7.5. the crystals belong to space group C222(1), with unit-cell dimensions a = 160.2, b = 175.6, c = 255.5 A, and diffract to 3.2 A resolution
-
sitting drop vapor diffusion method, crystal structure determined at 3.0 A resolution