3.8.1.7: 4-chlorobenzoyl-CoA dehalogenase

This is an abbreviated version!
For detailed information about 4-chlorobenzoyl-CoA dehalogenase, go to the full flat file.

Word Map on EC 3.8.1.7

3.8.1.7

dehalogenation

4-hydroxybenzoyl-coa

meisenheimer

4-hydroxybenzoate

thioesterase

4-hba-coa

raman

arthrobacter

dechlorination

dunaway-mariano

homotetramer

expulsion

pi-electrons

4-position

crotonase

Reaction

Synonyms

4-CBA-CoA dehalogenase, 4-CBCoA dehalogenase, 4-CBS-CoA dehalogenase, 4-chlorobenzoate-CoA-dehalogenase, 4-chlorobenzoate-coenzyme A dehalogenase, 4-chlorobenzoyl CoA dehalogenase, 4-chlorobenzoyl-CoA dehalogenase, 4-chlorobenzoyl-coenzyme A dehalogenase, CHD, dehalogenase, 4-chlorobenzoyl coenzyme A, dehalogenase, 4-chlorobenzoyl coenzyme A (Pseudomonas strain CBS-3 clone pMMB22 reduced), FcbB

ECTree

3 Hydrolases

3.8 Acting on halide bonds

3.8.1 In carbon-halide compounds

3.8.1.7 4-chlorobenzoyl-CoA dehalogenase

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Results	in table
344	AA Sequence
2	CAS Registry Number
7	Cloned(Commentary)
2	Cofactor
2	Crystallization (Commentary)
4	General Information
1	General Stability
39	Inhibitors
1	kcat/KM [mM/s]
27	Ki Value [mM]
50	KM Value [mM]
2	Metals/Ions
14	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
104	Organism
4	Pathway
8	pH Optimum
3	pH Range
8	pH Stability
2	pI Value
60	Protein Variants
7	Purification (Commentary)
14	Reaction
6	Reaction Type
39	Reference
1	Renatured (Commentary)
2	Source Tissue
21	Specific Activity [micromol/min/mg]
3	Storage Stability
85	Substrates and Products (Substrate)
20	Subunits
31	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
51	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 3.8.1.7 - 4-chlorobenzoyl-CoA dehalogenase

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0.007

Arthrobacter sp.

time elapsed at 45°C, 1020 min, recovery 1.7%

685426

0.08

Arthrobacter sp.

time elapsed at 45°C, 120 min, recovery 19.9%

685426

0.082

3 entries

0.194

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase following exposure to elevated temperature, 55°C, activity after heating to 60°C 0.081, recovery 20.1%

685426

0.243

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase following exposure to elevated temperature, 20°C, activity after heating to 60°C 0.038, recovery 9.5%

685426

0.301

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase following exposure to elevated temperature, 30°C, activity after heating to 60°C 0.051, recovery 12.7%

685426

0.349

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase following exposure to elevated temperature, 50°C, activity after heating to 60°C 0.082, recovery 20.4%

685426

0.36

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase following exposure to elevated temperature, 40°C, activity after heating to 60°C 0.055, recovery 13.7%

685426

0.363

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase after return from pH 5.2 to pH 7.4, incubation time 7 min, recovery 89%

685426

0.365

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase after return from pH 10.1 to pH 7.4, incubation time 7 min, recovery 90%

685426

0.402

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase following exposure to elevated temperature, 45°C, activity after heating to 60°C 0.083, recovery 20.6%

685426

0.407

Arthrobacter sp.

renaturation of 4-CBCoA dehalogenaase after return from pH 10.1 to pH 7.4, incubation time 17 min, recovery 99%

0.41

1.5

purified wild-type enzyme

2.25

3.61

pH 7.5, 30°C

additional information

2 entries