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3.8.1.7: 4-chlorobenzoyl-CoA dehalogenase

This is an abbreviated version!
For detailed information about 4-chlorobenzoyl-CoA dehalogenase, go to the full flat file.

Word Map on EC 3.8.1.7

Reaction

4-chlorobenzoyl-CoA
+
H2O
=
4-hydroxybenzoyl CoA
 +
chloride

Synonyms

4-CBA-CoA dehalogenase, 4-CBCoA dehalogenase, 4-CBS-CoA dehalogenase, 4-chlorobenzoate-CoA-dehalogenase, 4-chlorobenzoate-coenzyme A dehalogenase, 4-chlorobenzoyl CoA dehalogenase, 4-chlorobenzoyl-CoA dehalogenase, 4-chlorobenzoyl-coenzyme A dehalogenase, CHD, dehalogenase, 4-chlorobenzoyl coenzyme A, dehalogenase, 4-chlorobenzoyl coenzyme A (Pseudomonas strain CBS-3 clone pMMB22 reduced), FcbB

ECTree

     3 Hydrolases
         3.8 Acting on halide bonds
             3.8.1 In carbon-halide compounds
                3.8.1.7 4-chlorobenzoyl-CoA dehalogenase

Reference

topprint

Reference on EC 3.8.1.7 - 4-chlorobenzoyl-CoA dehalogenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Chang, K.H.; Liang, P.H.; Beck, W.; Scholten, J.D.; Dunaway-Mariano, D.
Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3
Biochemistry
31
5605-5610
1992
Pseudomonas sp., Pseudomonas sp. CBS-3
Manually annotated by BRENDA team
Dunaway-Mariano, D.; Babbitt, P.C.
On the origins and functions of the enzymes of the 4-chlorobenzoate to 4-hydroxybenzoate converting pathway
Biodegradation
5
259-276
1994
Arthrobacter sp., Pseudomonas sp., Arthrobacter sp. 4-CB1, Pseudomonas sp. CBS-3
Manually annotated by BRENDA team
Crooks, G.P.; Copley, S.D.
Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1
Biochemistry
33
11645-11649
1994
Arthrobacter sp., Arthrobacter sp. 4-CB1
Manually annotated by BRENDA team
Liang, P.H.; Yang, G.; Dunaway-Mariano, D.
Specificity of 4-chlorobenzoyl coenzyme A dehalogenase catalyzed dehalogenation of halogenated aromatics
Biochemistry
32
12245-12250
1993
Pseudomonas sp., Pseudomonas sp. CBS-3
Manually annotated by BRENDA team
Taylor, K.L.; Xiang, H.; Liu, R.Q.; Yang, G.; Dunaway-Mariano, D.
Investigation of substrate activation by 4-chlorobenzoyl-coenzyme A dehalogenase
Biochemistry
36
1349-1361
1997
Pseudomonas sp., Pseudomonas sp. CBS-3
Manually annotated by BRENDA team
Benning, M.M.; Taylor, K.L.; Liu, R.Q.; Yang, G.; Xiang, H.; Wesenberg, G.; Dunaway-Mariano, D.; Holden, H.M.
Structure of 4-chlorobenzoyl coenzyme A dehalogenase determined to 1.8 A resolution: an enzyme catalyst generated via adaptive mutation
Biochemistry
35
8103-8109
1996
Pseudomonas sp. (A5JTM5), Pseudomonas sp., Pseudomonas sp. CBS-3 (A5JTM5)
Manually annotated by BRENDA team
Löffler, F.; Lingens, F.; Muller, R.
Dehalogenation of 4-chlorobenzoate. Characterisation of 4-chlorobenzoyl-coenzyme A dehalogenase from Pseudomonas sp. CBS3
Biodegradation
6
203-212
1995
Pseudomonas sp., Pseudomonas sp. CBS-3
Manually annotated by BRENDA team
Yang, G.; Liang, P.H.; Dunaway-Mariano, D.
Evidence for nucleophilic catalysis in the aromatic substitution reaction catalyzed by 4-chlorobenzoyl-coenzyme A dehalogenase
Biochemistry
33
8527-8531
1994
Pseudomonas sp.
Manually annotated by BRENDA team
Yang, G.; Liu, R.Q.; Taylor, K.L.; Xiang, H.; Price, J.; Dunaway-Mariano, D.
Identification of active site residues essential to 4-chlorobenzoyl-coenzyme A dehalogenase catalysis by chemical modification and site directed mutagenesis
Biochemistry
35
10879-10885
1996
Pseudomonas sp.
Manually annotated by BRENDA team
Crooks, G.P.; Xu, L.; Barkley, R.M.; Copley, S.D.
Exploration of possible mechanisms for 4-chlorobenzoyl CoA dehalogenase: evidence for an aryl-enzyme intermediate
J. Am. Chem. Soc.
117
10791-10798
1995
Arthrobacter sp., Arthrobacter sp. 4-CB1
-
Manually annotated by BRENDA team
Zhang, W.; Wei, Y.; Luo, L.; Taylor, K.L.; Yang, G.; Dunaway-Mariano, D.; Benning, M.M.; Holden, H.M.
Histidine 90 function in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis
Biochemistry
40
13474-13482
2001
Pseudomonas sp. (A5JTM5)
Manually annotated by BRENDA team
Luo, L.; Taylor, K.L.; Xiang, H.; Wei, Y.; Zhang, W.; Dunaway-Mariano, D.
Role of active site binding interactions in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis
Biochemistry
40
15684-15692
2001
Pseudomonas sp.
Manually annotated by BRENDA team
Dong, J.; Lu, X.; Wei, Y.; Luo, L.; Dunaway-Mariano, D.; Carey, P.R.
The strength of dehalogenase-substrate hydrogen bonding correlates with the rate of Meisenheimer intermediate formation
Biochemistry
42
9482-9490
2003
Pseudomonas sp., Pseudomonas sp. CBS-3
Manually annotated by BRENDA team
Xu, D.; Guo, H.; Gao, J.; Cui, Q.
A QM/MM study of a nucleophilic aromatic substitution reaction catalyzed by 4-chlorobenzoyl-CoA dehalogenase
Chem. Commun. (Camb.)
2004
892-893
2004
Bacteria
-
Manually annotated by BRENDA team
Lau, E.Y.; Bruice, T.C.
The active site dynamics of 4-chlorobenzoyl-CoA dehalogenase
Proc. Natl. Acad. Sci. USA
98
9527-9532
2001
Pseudomonas sp., Pseudomonas sp. CBS-3
Manually annotated by BRENDA team
Zhou, L.; Marks, T.S.; Poh, R.P.; Smith, R.J.; Chowdhry, B.Z.; Smith, A.R.
The purification and characterisation of 4-chlorobenzoate:CoA ligase and 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain TM-1
Biodegradation
15
97-109
2004
Arthrobacter sp., Arthrobacter sp. TM-1
Manually annotated by BRENDA team
Wu, J.; Xu, D.; Lu, X.; Wang, C.; Guo, H.; Dunaway-Mariano, D.
Contributions of long-range electrostatic interactions to 4-chlorobenzoyl-CoA dehalogenase catalysis: a combined theoretical and experimental study
Biochemistry
45
102-112
2006
Pseudomonas sp.
Manually annotated by BRENDA team
Xu, D.; Guo, H.
Electrostatic influence of active-site waters on the nucleophilic aromatic substitution catalyzed by 4-chlorobenzoyl-CoA dehalogenase
FEBS Lett.
579
4249-4253
2005
Pseudomonas sp. (A5JTM5)
Manually annotated by BRENDA team
Xu, D.; Wei, Y.; Wu, J.; Dunaway-Mariano, D.; Guo, H.; Cui, Q.; Gao, J.
QM/MM studies of the enzyme-catalyzed dechlorination of 4-chlorobenzoyl-CoA provide insight into reaction energetics
J. Am. Chem. Soc.
126
13649-13658
2004
Pseudomonas sp. (A5JTM5)
Manually annotated by BRENDA team
Dong, J.; Luo, L.; Dunaway-Mariano, D.; Carey, P.R.
Raman evidence for product binding to the enzyme W137F 4-chlorobenzoyl-CoA dehalogenase in two conformational states
J. Raman Spectros.
36
320-325
2005
Pseudomonas sp.
-
Manually annotated by BRENDA team
Zhou, L.; Poh, R.P.; Marks, T.S.; Chowdhry, B.Z.; Smith, A.R.
Structure and denaturation of 4-chlorobenzoyl coenzyme A dehalogenase from Arthrobacter sp. strain TM-1
Biodegradation
19
65-75
2008
Arthrobacter sp.
Manually annotated by BRENDA team
Chae, J.C.; Song, B.; Zylstra, G.J.
Identification of genes coding for hydrolytic dehalogenation in the metagenome derived from a denitrifying 4-chlorobenzoate degrading consortium
FEMS Microbiol. Lett.
281
203-209
2008
consortium cosmid clone pGZ1
Manually annotated by BRENDA team
Wang, G.; Li, R.; Li, S.; Jiang, J.
A novel hydrolytic dehalogenase for the chlorinated aromatic compound chlorothalonil
J. Bacteriol.
192
2737-2745
2010
Pseudomonas sp. (C7EW69), Pseudomonas sp., Pseudomonas sp. CTN-3 (C7EW69)
Manually annotated by BRENDA team
Plotnikova, E.; Solyanikova, I.; Egorova, D.; Shumkova, E.; Golovleva, L.
Degradation of 4-chlorobiphenyl and 4-chlorobenzoic acid by the strain Rhodococcus ruber P25
Microbiology
81
143-153
2012
Rhodococcus ruber, Rhodococcus ruber P25
Manually annotated by BRENDA team