3.8.1.7: 4-chlorobenzoyl-CoA dehalogenase

This is an abbreviated version!
For detailed information about 4-chlorobenzoyl-CoA dehalogenase, go to the full flat file.

Reaction

Synonyms

4-CBA-CoA dehalogenase, 4-CBCoA dehalogenase, 4-CBS-CoA dehalogenase, 4-chlorobenzoate-CoA-dehalogenase, 4-chlorobenzoate-coenzyme A dehalogenase, 4-chlorobenzoyl CoA dehalogenase, 4-chlorobenzoyl-CoA dehalogenase, 4-chlorobenzoyl-coenzyme A dehalogenase, CHD, dehalogenase, 4-chlorobenzoyl coenzyme A, dehalogenase, 4-chlorobenzoyl coenzyme A (Pseudomonas strain CBS-3 clone pMMB22 reduced), FcbB

ECTree

     3 Hydrolases

         3.8 Acting on halide bonds

             3.8.1 In carbon-halide compounds

                3.8.1.7 4-chlorobenzoyl-CoA dehalogenase

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Results	in table
344	AA Sequence
2	CAS Registry Number
7	Cloned(Commentary)
2	Cofactor
2	Crystallization (Commentary)
4	General Information
1	General Stability
39	Inhibitors
1	kcat/KM [mM/s]
27	Ki Value [mM]
50	KM Value [mM]
2	Metals/Ions
14	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
104	Organism
4	Pathway
8	pH Optimum
3	pH Range
8	pH Stability
2	pI Value
60	Protein Variants
7	Purification (Commentary)
14	Reaction
6	Reaction Type
39	Reference
1	Renatured (Commentary)
2	Source Tissue
21	Specific Activity [micromol/min/mg]
3	Storage Stability
85	Substrates and Products (Substrate)
20	Subunits
31	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
51	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.8.1.7 - 4-chlorobenzoyl-CoA dehalogenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

2,4,5,6-tetrachloroisophthalonitrile + H2O

4-hydroxy-trichloroisophthalonitrile + chloride

2 entries

4-chlorobenzoyl-CoA + H2O

4-hydroxybenzoyl-CoA + chloride

6 entries

additional information

?

-

2 entries

2,4,5,6-tetrachloroisophthalonitrile + H2O

4-hydroxy-trichloroisophthalonitrile + chloride

Pseudomonas sp.

C7EW69

-

719717

-

-

?

2,4,5,6-tetrachloroisophthalonitrile + H2O

4-hydroxy-trichloroisophthalonitrile + chloride

Pseudomonas sp. CTN-3

C7EW69

-

719717

-

-

?

4-chlorobenzoyl-CoA + H2O

4-hydroxybenzoyl-CoA + chloride

Arthrobacter sp.

-

-

685426

-

-

?

4-chlorobenzoyl-CoA + H2O

4-hydroxybenzoyl-CoA + chloride

Bacteria

-

-

655227

-

-

?

4-chlorobenzoyl-CoA + H2O

4-hydroxybenzoyl-CoA + chloride

Pseudomonas sp.

-

-

654718, 657187

-

-

?

4-chlorobenzoyl-CoA + H2O

4-hydroxybenzoyl-CoA + chloride

Pseudomonas sp.

A5JTM5

-

654585

-

-

?

4-chlorobenzoyl-CoA + H2O

4-hydroxybenzoyl-CoA + chloride

Pseudomonas sp.

-

degradation in soil, pathway overview

654589

-

-

?

4-chlorobenzoyl-CoA + H2O

4-hydroxybenzoyl-CoA + chloride

Pseudomonas sp. CBS-3

-

-

654718, 657187

-

-

?

additional information

?

-

Rhodococcus ruber

-

degradation via the stages of formation of intermediates, 4-hydroxybenzoate and protocatechuic acid, to compounds of the basic metabolism is controlled by the fcbA and fcbB genes encoding 4-chlorobenzoate-CoA ligase and 4-chlorobenzoate-CoA-dehalogenase, respectively, overview

720401

-

-

?

additional information

?

-

Rhodococcus ruber P25

-

degradation via the stages of formation of intermediates, 4-hydroxybenzoate and protocatechuic acid, to compounds of the basic metabolism is controlled by the fcbA and fcbB genes encoding 4-chlorobenzoate-CoA ligase and 4-chlorobenzoate-CoA-dehalogenase, respectively, overview

720401

-

-

?