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3.7.1.8: 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

This is an abbreviated version!
For detailed information about 2,6-dioxo-6-phenylhexa-3-enoate hydrolase, go to the full flat file.

Word Map on EC 3.7.1.8

Reaction

2,6-dioxo-6-phenylhexa-3-enoate
+
H2O
=
benzoate
+
2-oxopent-4-enoate

Synonyms

2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoic acid hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2, 4-dienoate hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase, 2-hydroxy-6-oxo-6-phenylhexa-2,4-dieonic acid hydrolase, 6-phenyl HODA hydrolase, BphD, BphD enzyme, BphDP6, CarC, HOHPDA hydrolase, HOPD hydrolase, HOPDA hydrolase, HPDA hydrolase, HsaD, hydrolase, 2,6-dioxo-6-phenylhexa-3-enoate, LigY, MCP hydrolase, meta-cleavage product hydrolase, MhpC

ECTree

     3 Hydrolases
         3.7 Acting on carbon-carbon bonds
             3.7.1 In ketonic substances
                3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

Turnover Number

Turnover Number on EC 3.7.1.8 - 2,6-dioxo-6-phenylhexa-3-enoate hydrolase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.13 - 33.7
(2E,4E)-2-hydroxy-6-(4-chlorophenyl)-6-oxohexa-2,4-dienoic acid
4.18 - 7.6
(2E,4E)-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
1.74 - 2.1
(2E,4E)-6-(2-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid
29
(2E,4E)-6-(3,4-dichlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid
-
-
11.2
(2E,4E)-6-(3,5-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid
-
-
3.9 - 15.3
(2E,4E)-6-(3-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid
0.0055
(2E,4Z)-2,4-dihydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
-
-
0.00059
(2E,4Z)-4-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
-
-
1.03 - 1.53
(2E,4Z)-5-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
0.0089 - 0.0172
(2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
0.13 - 9.9
2,6-dioxo-6-phenylhexa-3-enoate
1300
2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoic acid
-
-
11.61
2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate
A0A0H0ZQK0
pH 7.0, 30°C
1.11
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
-
at 60°C
0.066 - 26
2-Hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid
9.7
4,11-dicarboxy-8-hydroxy-9-methoxy-2-hydroxy-6-oxo-6-phenyl-hexa-2,4-dienoate
pH 7, 25°C
6.3
4-nitrophenyl benzoate
-
pH 7.5, 25°C
0.33
8-(2-chlorophenyl)-2-hydroxy-5-methyl-6-oxoocta-2,4-dienoic acid
pH 7.5, 25°C
0.0009 - 6.5
ethyl-2-acetoxy-6-keto-6-phenylhexa-2,4-dienoate
0.009 - 12
meta-ring fission intermediate
-
additional information
additional information
-