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3.6.1.42: guanosine-diphosphatase

This is an abbreviated version!
For detailed information about guanosine-diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.42

Reaction

GDP
+
H2O
=
GMP
 +
phosphate

Synonyms

APY1, DIPP1, E-NTPDase, ecto-nucleoside triphosphate diphosphohydrolase, gda1p (GDA1 gene product), Gdap1, Gdp1p, GDPase, guanosine diphosphatase, KlGdap1, phosphatase, guanosine di-, UDPase

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.42 guanosine-diphosphatase

Cloned

Cloned on EC 3.6.1.42 - guanosine-diphosphatase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amino acid sequence determination and analysis, functional complementation of a Saccharomyces GDPase null mutant
DNA sequence determination and analysis, enzyme can complement and restore activity in Saccharomyces cerevisiae deletion mutant gda1, complementation of N-glycosylation defects
expressed in HEK-293 cells
-
normal and transforming PCPH proteins: PCPH, PCPH proto-oncogene and mt-PCPH, PCPH oncogene having guanosine diphosphatase activity
normal and transforming PCPH proteins: PCPH, PCPH proto-oncogene and mt-PCPH, PCPH oncogene having guanosine diphosphatase activity, expression in Escherichia coli BL21, DE3
-
overexpression in Schizosaccharomyces pombe, functional complementation of a Saccharomyces cerevisiae enzyme mutant defective in chitinase O-mannosylation
-
overexpression of GDA1 gene
-