3.6.1.24: nucleoside phosphoacylhydrolase

This is an abbreviated version!
For detailed information about nucleoside phosphoacylhydrolase, go to the full flat file.

Reaction

Hydrolyses mixed phospho-anhydride bonds =

ECTree

     3 Hydrolases

         3.6 Acting on acid anhydrides

             3.6.1 In phosphorus-containing anhydrides

                3.6.1.24 nucleoside phosphoacylhydrolase

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Results	in table
2	Activating Compound
1	AA Sequence
1	CAS Registry Number
1	General Stability
7	Inhibitors
5	KM Value [mM]
1	Localization
1	Metals/Ions
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	Oxidation Stability
1	pH Optimum
1	pH Range
1	pH Stability
1	Purification (Commentary)
1	Reaction
1	Reaction Type
1	Reference
1	Renatured (Commentary)
2	Specific Activity [micromol/min/mg]
1	Storage Stability
8	Substrates and Products (Substrate)
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 3.6.1.24 - nucleoside phosphoacylhydrolase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

acetyl adenylate + H2O

?

Escherichia coli

-

-

209999

-

-

?

adenosine 5'-p-nitrophenylphosphate + H2O

p-nitrophenol + AMP

Escherichia coli

-

-

209999

-

209999

?

cytidine 5'-p-nitrophenylphosphate + H2O

p-nitrophenol + CMP

Escherichia coli

-

-

209999

-

209999

?

guanosine 5'-p-nitrophenylphosphate + H2O

p-nitrophenol + GMP

Escherichia coli

-

-

209999

-

209999

?

methionyl adenylate + H2O

?

Escherichia coli

-

-

209999

-

-

?

p-nitrophenyl 5'-nucleotides + H2O

p-nitrophenol + nucleoside phosphate

Escherichia coli

-

hydrolysis A,C,G,U,T nucleotides

209999

-

209999

?

thymidine 5'-p-nitrophenylphosphate + H2O

p-nitrophenol + TMP

Escherichia coli

-

-

209999

-

209999

?

uridine 5'-p-nitrophenylphosphate + H2O

p-nitrophenol + UMP

Escherichia coli

-

-

209999

-

209999

?