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3.6.1.13: ADP-ribose diphosphatase

This is an abbreviated version!
For detailed information about ADP-ribose diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.13

Reaction

ADP-D-ribose
+
H2O
=
AMP
+
D-ribose 5-phosphate

Synonyms

adenosine 5'-diphosphosugar pyrophosphatase, adenosine diphosphoribose pyrophosphatase, ADP-ribose diphosphatase, ADP-ribose hydrolase, ADP-ribose phosphohydrolase, ADP-ribose pyrophosphatase, ADP-ribose pyrophosphatase Sll1054, ADP-ribose pyrophosphatase Slr0920, ADP-ribose pyrophosphatase Slr1134, ADP-ribose pyrophosphatase-I, ADP-ribose/CDP-alcohol diphosphatase, ADP-ribose/NADH pyrophosphohydrolase, ADPR pyrophosphatase, ADPR-PPase, ADPRase, ADPRase-I, ADPRibase, ADPRibase-Mn, ADPribose pyrophosphatase, Adprm, AT4G12720, AtNUDT10, AtNUDT2, AtNUDT6, AtNUDT7, AtNUDX7, cADPR phosphohydrolase, CinA, cyclic ADPR phosphohydrolase, DR2204, EcADPRase, mNUDT5 protein, More, MT1739, MtADPRase, MutT/nudix family protein, NadM-Nudix, Ndx2, Ndx4, NMN adenylyltransferase/ADP-ribose pyrophosphatase, Nudix hydrolase, Nudix hydrolase 7, NUDT5, NUDT5 protein, NUDT9, NUDT9 protein, NUDT9alpha protein, NUDX2, NUDX7, NuhA, pyrophosphatase, adenosine diphosphoribose, submicromolar-K(m) ADP-ribose pyrophosphatase, TtADPRase, YSA1H, zgc:64213

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.13 ADP-ribose diphosphatase

Activating Compound

Activating Compound on EC 3.6.1.13 - ADP-ribose diphosphatase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
nitric oxide
-
NO stimulates non-enzymatic ADP-ribosylation, at cysteine residues in the presence of reductant, of NUDT5 using ADP-ribose and consequently activates its ADPRase activity. ADPRase activity in J774 macrophage cells is increased by the treatment with SNP, an exogenous NO generator, or TNF-alpha/IFN-gamma, endogenous NO inducers. NO has a regulatory role, overview